RSS-Feed abonnieren
Bitte kopieren Sie die angezeigte URL und fügen sie dann in Ihren RSS-Reader ein.
https://www.thieme-connect.de/rss/thieme/de/10.1055-s-00000084.xml
Synthesis 2000; 2000(1): 84-90
DOI: 10.1055/s-2000-6222
DOI: 10.1055/s-2000-6222
paper
© Georg Thieme Verlag, Rüdigerstr. 14, 70469 Stuttgart, Germany. All rights reserved. This journal, including all individual contributions and illustrations published therein, is legally protected by copyright for the duration of the copyright period. Any use, exploitation or commercialization outside the narrow limits set by copyright legislation, without the publisher's consent, is illegal and liable to criminal prosecution. This applies in particular to photostat reproduction, copying, cyclostyling, mimeographing or duplication of any kind, translating, preparation of microfilms, and electronic data processing and storage.
A Facile Synthesis of Amides from 9-Fluorenylmethyl Carbamates and Acid Derivatives
Weitere Informationen
Publikationsverlauf
Publikationsdatum:
31. Dezember 2000 (online)
![](https://www.thieme-connect.de/media/synthesis/200001/lookinside/thumbnails/10.1055-s-2000-6222-1.jpg)
A mild and convenient one-pot procedure for the synthesis of amides from 9-fluorenylmethyl carbamates and acids using potassium fluoride, triethylamine and various coupling reagents in DMF at room temperature is described. The scope of this procedure was also tested in the coupling of a variety of 9-fluorenylmethyloxycarbonyl-protected amines with active moieties such as anhydrides, acyl imidazolides, activated esters, tosyl chlorides, and acyl halides.
9-fluorenylmethyl carbamates - peptide synthesis - potassium fluoride - BOP-Cl - amides - acids - protecting groups