Download PDF
Synthesis 2000; 2000(3): 435-441
DOI: 10.1055/s-2000-6335
paper
© Georg Thieme Verlag, Rüdigerstr. 14, 70469 Stuttgart, Germany. All rights reserved. This journal, including all individual contributions and illustrations published therein, is legally protected by copyright for the duration of the copyright period. Any use, exploitation or commercialization outside the narrow limits set by copyright legislation, without the publisher's consent, is illegal and liable to criminal prosecution. This applies in particular to photostat reproduction, copying, cyclostyling, mimeographing or duplication of any kind, translating, preparation of microfilms, and electronic data processing and storage.

An Expedient Synthesis of Novel [1,2,4]Triazolo[3,2-d][1,5]Benzothiazepine Derivatives

Xianjun Liu* , Quanrui Wang, Yi Liu, Yubo Fan, Zongbiao Ding
  • *Department of Chemistry, Fudan University, 200433 Shanghai, P. R. China; Fax +86 (21) 65 64 17 40; E-mail: qrwangb@online.sh.cn
Further Information

Publication History

Publication Date:
31 December 2000 (online)

  PDF Download  Permissions and Reprints All articles of this category

The synthesis of a series of unprecedented tricyclic heterocycles, 1,2,4-triazolo[3,2-d][1,5]benzothiazepine 6-oxides (5a-i), was accomplished via cycloaddition of the allene-like cations 3, derived from thiochroman-4-one arylhydrazones, to the triple bond of nitriles and ensuing ring expansion annulation. The structure of one product (5h) has been unambiguously determined by X-ray diffraction analysis.

allene-like cations - cycloaddition - nitriles - ring expansion - 1,2,4-triazolo[3,2-d][1,5]benzothiazepine 6-oxides