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Synthesis 2000; 2000(9): 1310-1314
DOI: 10.1055/s-2000-6417
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Synthesis of (S,S)- and (R,R)-2-Amino-3-methylaminobutanoic Acid (AMBA)

D. David Hennings, Robert M. Williams
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Publication Date:
31 December 2000 (online)

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The synthesis and characterization of (S,S)- and (R,R)-2-amino-3-methylaminobutanoic acid starting from tert-butyl crotonate is described.

(S,S)-2-amino-3-methylaminobutanoic acid - (R,R)-2-amino-3-methylaminobutanoic acid - AMBA - Sharpless asymmetric aminohydroxylation - azide displacement

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