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Synthesis 2000; 2000(9): 1295-1298
DOI: 10.1055/s-2000-6426
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Synthesis of Optically Active α-Amino Acids Containing Pyrazolyl Ring as Substituent

Lidia De Luca* , Giampaolo Giacomelli, Andrea Porcheddu, Anton Mario Spanedda, Massimo Falorni
  • *Dipartimento di Chimica, Università di Sassari, I-07100 Sassari, Italy; Fax + 39(0 79)21 20 69; E-mail: ggp@ssmain.uniss.it
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Publikationsdatum:
31. Dezember 2000 (online)

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Starting from commercially available l-serine, some pyrazolyl oxazolidines have been prepared and transformed into novel chiral α-amino acids, containing a pyrazole ring, which can be regarded as building blocks for peptidomimetics.

amino acids - cycloadditions - heterocycles - hydrazones - regioselectivity