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Synlett 2000; 2000(6): 0823-0825
DOI: 10.1055/s-2000-6691
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Syntheses of Sialyl Lewis A Glycopeptides - A Partial Sequence of the P-Selectin Ligand PSGL-1

Karen Peilstöcker* , Horst Kunz
  • *Institut für Organische Chemie, Johannes Gutenberg-Universität Mainz, Duesbergweg 10 - 14, D-55099 Mainz, Germany; Fax +49 6131 39-22334; E-mail: hokunz@mail.uni-mainz.de
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Publication Date:
31 December 2000 (online)

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A glycopeptide partial sequence of the binding region of the P-selectin glycoprotein ligand PSGL-1 in which the O-glycosyl threonine is substituted by a Sialyl Lewis A asparagine moiety was synthesized on solid-phase using the allylic HYCRON anchoring technique.

glycopeptides - solid-phase synthesis - Sialyl Lewis A asparagine - P-selectin ligand (PSGL-1) - allylic anchor