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Synlett 2000; 2000(6): 0801-0804
DOI: 10.1055/s-2000-6719
DOI: 10.1055/s-2000-6719
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Electrophilic Aromatic Substitution by Use of N-Tosyliminium Ions; Elaboration of 3-Aryl Tetrahydroisoquinolines
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Publication History
Publication Date:
31 December 2000 (online)

The elaboration of 3-aryltetrahydroisoquinoline derivatives by electrophilic aromatic substitution of polysubstituted phenols and phenyl ethers with Lewis acid-generated tosyliminium ions is reported.
N-tosyliminium ions - phenyl ethers - Schefferine - 3-aryltetrahydroisoquinolines - electrophilic aromatic substitution