Download PDF
Synlett 2000; 2000(10): 1503-1505
DOI: 10.1055/s-2000-7653
letter
© Georg Thieme Verlag, Rüdigerstr. 14, 70469 Stuttgart, Germany. All rights reserved. This journal, including all individual contributions and illustrations published therein, is legally protected by copyright for the duration of the copyright period. Any use, exploitation or commercialization outside the narrow limits set by copyright legislation, without the publisher's consent, is illegal and liable to criminal prosecution. This applies in particular to photostat reproduction, copying, cyclostyling, mimeographing or duplication of any kind, translating, preparation of microfilms, and electronic data processing and storage.

Synthesis of Sb-chiral Organoantimony(III) Compounds: Stepwise Nucleophilic Displacement Reaction of Tribromostibane via a Bisethynylstibane Intermediate

Naoki Kakusawa* , Tomoyoshi Ikeda, Atsuko Osada, Jyoji Kurita, Takashi Tsuchiya
  • *Faculty of Pharmaceutical Sciences, Hokuriku University, Kanazawa 920-1181, Japan; Fax + 81-76-229-1165; E-mail: j-kurita@hokuriku-u.ac.jp
Further Information

Publication History

Publication Date:
31 December 2000 (online)

  PDF Download  Permissions and Reprints All articles of this category

Treatment of bis(1-phenylethynyl)-p-tolylstibanes 2 with Grignard reagents resulted in nucleophilic displacement of one ethynyl group on 2 to afford the monoethynyl compounds 3 on which the remaining ethynyl group could be replaced with other substituents by treatment with Grignard or organolithium reagents. These stepwise reactions provide an efficient method for the preparation of a wide range of Sb-chiral organoantimony(III) compounds.

antimony - ethynylstibanes - nucleophilic substitution - Sb-chiral stibane - Grignard reagent