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Synlett 2000; 2000(11): 1581-1584
DOI: 10.1055/s-2000-7915
DOI: 10.1055/s-2000-7915
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The First Pd-Catalyzed Aminations of 4-Chloro-3(2H)-Pyridazinones
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Publication History
Publication Date:
31 December 2000 (online)
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Palladium-catalyzed amination on 4-chloro-3(2H)-pyridazinones has been achieved for the first time. Anilines, 2-aminopyridine and benzophenone imine react in good to excellent yields. Excess of alkali metal carbonate base is crucial for the reaction with lower catalyst loadings.
palladium - catalysis - aminations - chloropyridazinones - anilines