Download PDF
Synthesis 2000; 2000(12): 1709-1712
DOI: 10.1055/s-2000-8208
paper
© Georg Thieme Verlag, Rüdigerstr. 14, 70469 Stuttgart, Germany. All rights reserved. This journal, including all individual contributions and illustrations published therein, is legally protected by copyright for the duration of the copyright period. Any use, exploitation or commercialization outside the narrow limits set by copyright legislation, without the publisher's consent, is illegal and liable to criminal prosecution. This applies in particular to photostat reproduction, copying, cyclostyling, mimeographing or duplication of any kind, translating, preparation of microfilms, and electronic data processing and storage.

A Practical Synthesis of tert-Alkylamines via the Ritter Reaction with Chloroacetonitrile

Aigars Jirgensons* , Valerjans Kauss, Ivars Kalvinsh, Markus R. Gold
  • *Latvian institute of Organic Synthesis, 21 Aizkraukles Str., Riga, 1006, Latvia; Fax +3 71 (2) 7 82 81 14; E-mail: aigars@osi.lv
Further Information

Publication History

Publication Date:
31 December 2000 (online)

  PDF Download  Permissions and Reprints All articles of this category

Ritter reaction of tertiary alcohols with chloroacetonitrile and subsequent cleavage of chloroacetyl group in the resulting chloroacetamide with thiourea is an efficient procedure for synthesis of tert-alkylamines.

Ritter reaction - tertiary alcohols - amides - amines - cleavage