Planta Med 2000; 66(4): 380-381
DOI: 10.1055/s-2000-8542
Letter
Georg Thieme Verlag Stuttgart · New York

Xanthones in Cell Cultures of Hypericum androsaemum

Werner Schmidt1, 3 , Ahmed M. A. Abd El-Mawla1 , Jean-Luc Wolfender2 , Kurt Hostettmann2 , Ludger Beerhues1,*
  • 1 Institut für Pharmazeutische Biologie, Rheinische Friedrich-Wilhelms-Universität, Bonn, Germany
  • 2 Institut de Pharmacognosie et Phytochimie, Université de Lausanne, Lausanne, Switzerland
  • 3 Institute of Plant Sciences, Swiss Federal Institute of Technology, Zürich, Switzerland
Further Information

Publication History

Publication Date:
31 December 2000 (online)

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Abstract

Cell cultures of Hypericum androsaemum contain an array of prenylated xanthone aglycones and their glucosides, when grown in modified B5 medium in the dark. Derivatives of 1,3,6,7-tetrahydroxyxanthone prevail over compounds with the 1,3,5,6-oxygenation pattern. 1,7-Dihydroxyxanthone was also isolated. Xanthone accumulation parallels cell growth, is repressed by light and strongly influenced by the culture medium used.