Cytotoxic Neolignans from the Stem Wood of Machilus obovatifolia

Abstract

Four new cytotoxic neolignans, machilusol A (1), machilusol C (3), machilusol D (4), machilusol E (5) as well as two new inactive neolignans, machilusol B (2) and machilusol F (6), were isolated from the stem wood of Machilus obovatifolia. All structures were identified by means of spectroscopic analysis.

Key words

Machilus obovatifolia - Persea obovatifolia - Lauraceae, stem wood - neolignan - machilusol A - F - cytotoxicity

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