Planta Med 2000; 66(7): 647-650
DOI: 10.1055/s-2000-8623
Letter
Georg Thieme Verlag Stuttgart · New York

Antimicrobial Activity and Chemical Composition of the Bark Oil of Croton stellulifer, an Endemic Species from S. Tomé e Príncipe

Ana Paula Martins1 , Lígia R. Salgueiro1,*, Maria José Gonçalves1 , Roser Vila2 , Félix Tomi3 , Tomás Adzet2 , António Proença da Cunha1 , Salvador Cañigueral2 , Joseph Casanova3
  • 1 Lab. de Farmacognosia, Fac. de Farmácia, Universidade de Coimbra, Coimbra, Portugal
  • 2 Unitat de Farmacologia i Farmacognòsia, Fac. de Farmàcia, Universitat de Barcelona, Barcelona, Spain
  • 3 Equipe Chimie et Biomasse, URA CNRS 2053, Université de Corse, Ajaccio, France
Further Information

Publication History

Publication Date:
31 December 2000 (online)

Abstract

The composition and the antimicrobial activity of the bark oil of Croton stellulifer, an endemic and rare species of these islands (S. Tomé and Príncipe) are reported. Analysis was carried out by GC, GC/MS and 13C-NMR. The major constituents were α-phellandrene (15.4 - 18.6 %), p-cymene (14.4 - 17.7 %), linalool (12.0 - 12.6 %) and α-pinene (8.1 - 9.1 %). Kessane, a sesquiterpenoid oxide, not yet reported in the genus Croton, was identified by NMR. The essential oil of C. stellulifer was active against both bacterial and fungal strains, except Aspergillus niger.

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Prof. Dr. Lígia Salgueiro

Laboratório de Farmacognosia Faculdade de Farmácia de Coimbra

P-3000 Coimbra

Portugal

Email: ligia@gemini.ci.uc.pt

Phone: +351-239827126