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Synthesis 2001; 2001(2): 0221-0224
DOI: 10.1055/s-2001-10804
short paper
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A New and Convenient Synthesis of 3-Aryl-3-hydroxyisoindol-1-ones and Their Aza Analogs

Yuko Saito* , Takeshi Sakamoto, Yasuo Kikugawa
  • *Faculty of Pharmaceutical Sciences, Josai University, Sakado, Saitama 350-0295, Japan; Fax + 81(492)71 79 84; E-mail: kikugawa@josai.ac.jp
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Publication Date:
31 December 2001 (online)

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A simple and convenient synthesis of 3-aryl-3-hydroxyisoindol-1-ones and their aza analogs is described. The utility of this synthesis is demonstrated by the preparation of 4-arylphthalazinones and their aza analogs.

aluminum trichloride - hydrazides - hydroxyazaisoindolinones - pyrrolopyridinediones - 1-arylpyridopyridazinones