Exp Clin Endocrinol Diabetes 2001; Vol. 109(1): 2-7
DOI: 10.1055/s-2001-11009
Article

© Johann Ambrosius Barth

Representative data of iodine intake and urinary excretion in Germany

R. Gärtner 1 , F. Manz 2 , R. Grossklaus 3
  • 1 Medizinische Klinik der Ludwig-Maximilians-Universität, München
  • 2 Research Institute of Child Nutrition, Dortmund
  • 3 Bundesinstitut für Gesundheitlichen Verbraucherschutz und Veterinärmedizin, Berlin, Germany
Further Information

Publication History

Publication Date:
31 December 2001 (online)

Summary:

To evaluate the iodine supply of the German polulation, 2500 representative subjects older than 13 years were elected for answering a specific food questionnaire. In addition spot urine samples in 3 selected risk groups for iodine deficiency (574 adults aged 50-70 years, 769 conscripts, 886 pairs of mothers and newborns) from 26 representative regions were collected. Furthermore the circadian iodine excretion was measured in 24 h urine samples collected in 6 fractions per day in 4 subgroups (young and older males and females) of 91 controls and this 24 h iodine excretion related to iodine/creatinine ratio in these subgroups.

Mean estimated iodine intake was 119 μg/d in adults aged 50-70 years, 137 μg/d in conscripts, and 162 μg/d in mothers at still birth. The mean iodine concentration (iodine/creatinine ratio) was 9.4 μg/dl in 566 adults aged 50-70 years, 8.3 μg/dl in 772 conscripts and 5.6 μg/dl in 739 breast fed newborns. The mean daily iodine excretion was 134 μg/d in 278 men aged 50-70 years, 117 μg/d in 288 women aged 50-70 years, 125 μg/d in 772 conscripts and 74 μg/d in 53 breast-feeding mothers not using iodine tablets. These results show, that iodine intake in Germany has increased over the last years. The deficit in iodine intake with significant regional differences and defined risk groups for iodine deficiency (e.g. breast feeding mothers without iodine deficiency prophylaxis) is estimated to be about 30% of the recommended iodine intake.

References

  • 1 Anke M, Rother C, Arnhold W. et al .Die Iodversorgung Erwachsener Deutschlands in Abhängigkeit von Geschlecht, Zeit, Jahreszeit, Lebensraum, Stillperiode, Alter, Körpermasse und Form des Iodzusatzes. In: Köhrle J (ed) Mineralstoffe und Spurenelemente: Molekularbiologie, Interaktionen mit dem Hormonsystem, Analytik. Wissenschaftliche Verlagsgesellschaft, Stuttgart 207-231 1998
  • 2 Bauch K, Seitz W, Förster S. et al . Die interdisziplinäre Jodprophylaxe der ehemaligen DDR nach der Wiedervereinigung und der Stellenwert des jodierten Paketspeisesalzes für die Verbesserung der alimentären Jodversorgung.  Z Gesamte Inn Med. 44 595-634 1991; 
  • 3 Bittermann H, Großklaus R. Jodversorgung von Wehrpflichtigen in Deutschland. Medien & Medizin Verlagsgesellschaft, München 1-94 1999
  • 4 Deutsche Gesellschaft für Ernährung .Empfehlungen für die Nährstoffzufuhr. 5th ed. Umschau-Verlag, Frankfurt 65-67 1991
  • 5 Gärtner R, Bechtner G, Rafferzeder M, Greil W. Comparison of urinary iodine excretion and thyroid volume in students with or without constant iodized salt intake.  Exp Clin Endocrinol Diabetes. 105 (4) 43-45 1997; 
  • 6 Gutekunst R, Smolarek H, Hasenpusch U. et al . Goitre epidemiology: thyroid volume, iodine excretion, thyroglobulin and thyrotropin in Germany and Sweden.  Acta Endocrinol. 112 494-501 1986; 
  • 7 Gutekunst R, Magiera U, Teichert H-M. Jodmangel in der Bundesrepublik Deutschland.  Med Klin. 88 525-528 1993; 
  • 8 Hampel R, Kühlberg T, Zöllner H. et al . Alimentary supply of iodine in Germany.  Münch Med Wochenschr. 138 78-82 1996; 
  • 9 Kohlmeier M, Thefeld W, Stelte W. et al .Versorgung Erwachsener mit Mineralstoffen und Spurenelementen in der Bundesrepublik Deutschland. Fleck, Niederkleen C24-C81 1995
  • 10 Kübler W, Balzter H, Grimm R, Schek A, Schneider R. National food consumption survey (NVS) and co-operative study: nutrition survey and risk factors analysis (VERA): Synopsis and perspectives. Fleck, Niederkleen A36-A37 1997
  • 11 Liesenkötter K P, Kiebler A, Stach B, Willgerodt H, Grüters A. Small thyroid volumes and normal iodine excretion in Berlin schoolchildren indicate full normalization of iodine supply.  Exp Clin Endocrinol Diabetes 105 ((Suppl 4)) 46-50 1997; 
  • 12 Lorenz-Wawschinek O, Tiran B, Eber O, Langsteger W. Photometric determination of iodine in urine.  Exp Clin Endocrinol 102 ((Suppl 2)) 57-58 1994; 
  • 13 Malner C, Hehrmann R. Strumaepidemiologie im Raum Stuttgart und ihre Beziehung zur aktuellen Jodversorgung. In: Röher H-D, Weinheimer B (Hrsg) Schilddrüse: Therapie der Struma. de Gruyter, Berlin, New York 214-229 1991
  • 14 Manz F, Anke M, Bohnet H G, Gärtner R, Großklaus R, Klett M, Schneider R. Jod-Monitoring 1996. Nomos, Baden-Baden 1-264 1998
  • 15 Manz F. Is individual “spontaneous” drinking of children and adults the result of “programming” in early life?. In: Arnaud MJ (ed) Hydration throughout life. Libbey Eurotext, London 241-245 1998
  • 16 Meng W, Kirsch G. Alimentäre Jodversorgung und neonatales Hypothyreosescreening in Nordostdeutschland. In: Usadel K-H, Weinheimer B (eds) Schilddrüse 1995: Schilddrüsenerkrankungen in verschiedenen Lebensabschnitten. de Gruyter, Berlin 47-54 1996
  • 17 Metges C C, Greil W, Gärtner R. et al . Influence of knowledge on iodine content in foodstuffs and prophylactic usage of iodized salt on urinary iodine excretion and thyroid volume of adults in southern Germany.  Z Ernährungswiss. 35 6-12 1996; 
  • 18 Pfaff G, Georg T. Assessment of individual iodine intake by the adult population in the Potsdam region on the basis of sea fish and iodized salt consumption.  Z Ernährungswiss. 34 131-136 1995; 
  • 19 Pfaff G, Hesse V, Oehler K, Georg T, Boeing H. Alimentary iodine deficiency in the Potsdam region.  Z Ernährungswiss. 36 225-228 1997; 
  • 20 Prentice A M, Spaaij C JK, Goldberg G R. et al . Energy requirements of pregnant and lactating women.  Eur J Clin Nutr 50 ((Suppl 1)) S82-S111 1996; 
  • 21 Schoefield W N. Predicting basal metabolic rate, new standards and review of previous work.  Hum Nutr Clin Nutr 39C ((Suppl 1)) 5-41 1985; 
  • 22 Shetty P S, Henry C JK, Black A E, Prentice A M. Energy requirements of adults: an update on basal metabolic rates (BMRs) and physical activity levels (PALs).  Eur J Clin Nutr 50 ((Suppl 1)) S11-S23 1996; 
  • 23 Weber P, Manz F, Kersting M, Schöch G. Consumption of iodized salt and urinary excretion of sodium chloride.  Dtsch Med Wochenschr. 111 1916-1921 1986; 
  • 24 Willgerodt H, Keller E, Perschke C, Stach B. The status of iodine nutrition in newborn infants, schoolchildren, adolescents and adults in former East Germany.  Exp Clin Endocrinol Diabetes 105 ((Suppl 4)) 38-42 1997; 
  • 25 World Health Organization . Iodine deficiency disorders eliminated by the year 2000. Resolution of the 43rd World Health Assembly.  WHO Features. No. 143 1990; 
  • 26 World Health Organization .Trace elements in human nutrition and health. WHO, Geneva 49-71 1996

Prof. Dr. Roland Gärtner

Medizinische Klinik der LMU - Innenstadt

Ziemssenstraße 1

D-80336 München

Germany

Phone: +49-89-51 602 332

Fax: +49-89-51 604 430

Email: rgartner@medinn.med.uni-muenchen.de