Lithium Perchlorate Catalyzed Reactions of Indoles: An Expeditious Synthesis of Bis(indolyl)methanes

Jhillu S. Yadav; Basi V. Subba Reddy; Ch. V. S. R. Murthy; G. Mahesh Kumar; Ch. Madan

doi:10.1055/s-2001-12777

Subscribe to RSS

Please copy the URL and add it into your RSS Feed Reader.

https://www.thieme-connect.de/rss/thieme/en/10.1055-s-00000084.xml

Share / Bookmark

Facebook X Linkedin Weibo

Synthesis 2022(5): 0783-0787
DOI: 10.1055/s-2001-12777

PAPER

Lithium Perchlorate Catalyzed Reactions of Indoles: An Expeditious Synthesis of Bis(indolyl)methanes [1]

Jhillu S. Yadav*, Basi V. Subba Reddy, Ch. V. S. R. Murthy, G. Mahesh Kumar, Ch. Madan
Organic Chemistry Division-I, Indian Institute of Chemical Technology, Hyderabad-500 007, India
Fax: +91(40)7170512; e-Mail: yadav@iict.ap.nic.in;

Further Information

Publication History

Received 29 October 2000
Publication Date:
15 October 2004 (online)

Abstract
Full Text
References

Buy Article Permissions and Reprints All articles of this category

Abstract

Lithium perchlorate is found to catalyze efficiently the electrophilic substitution reactions of indoles with aldehydes and ketones in diethyl ether to afford the corresponding bis(indolyl)methanes in high yields. LiOTf is also found to be an efficient catalyst for the synthesis of these compounds.

Key words

lithium perchlorate - indoles - carbonyl compounds - bis(indolyl)methanes

1

IICT Communication No. 4566