Planta Med 2001; 67(4): 388-390
DOI: 10.1055/s-2001-14325
Letter

© Georg Thieme Verlag Stuttgart · New York

Phenolic Constituents of Ononis vaginalis Roots

Maged S. Abdel-Kader
  • Department of Pharmacognosy, College of Pharmacy, University of Alexandria, Alexandria, Egypt
Further Information

Publication History

June 15, 2000

September 1, 2000

Publication Date:
31 December 2001 (online)

Abstract

The ether soluble fraction of the roots of Ononis vaginalis Vahl. Symb. afforded three new compounds: 3-hydroxy-4,9-dimethoxycoumestan, maginaldehyde [2-(4-hydroxy-2-methoxyphenyl)-5,6-dimethoxy-3-benzofuran-carboxaldehyde] and 5,7,4′-trihydroxy-4-styrylcoumarin. In addition, four known pterocarpans; 3,4,9-trimethoxypterocarpan, maackiain, medicarpin and trifolirhizin were also isolated. The styrylcoumarin derivative showed significant antiviral activity against Herpes simplex type 1 and weak cytotoxicity.

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Maged S. Abdel-Kader

Department of Pharmacognosy

College of Pharmacy

Alexandria University

Alexandria

Egypt

Email: mpharm101@hotmail.com

Fax: +(203)483-3273