Download PDF
Dtsch Med Wochenschr 2001; 126(Suppl. Gastroenterol. 1): S1-S7
DOI: 10.1055/s-2001-14497
Supplement Gastroenterologie (1)
© Georg Thieme Verlag Stuttgart · New York

Diagnostik bei der Ulkuskrankheit:
Was ist nötig, was ist überflüssig?

Diagnosis of ulcerative disease: what is essential and what is not necessary?J. Mössner
  • Medizinische Klinik und Poliklinik II der Universität Leipzig
Further Information

Publication History

Publication Date:
11 September 2002 (online)

Also available at
    Permissions and Reprints

Überlegungen zur nötigen und überflüssigen Diagnostik des Ulkusleidens setzen eine Kenntnis der unterschiedlichen Pathomechanismen der Erkrankung, der Klinik, der Differentialdiagnose und der potenziellen Folgekomplikationen voraus.

Literatur

  • 1 Barenys M, Abad A, Pons J M, Moreno V, Rota R, Granados A, Admetlla M, Pique J M. Scoring system has better discriminative value than Helicobacter pylori testing in patients with dyspepsia in a setting with high prevalence of infection.  Eur J Gastroenterol Hepatol. 2000;  12 1275-1282
    Search in Google Scholar
  • 2 Bjorkman D J. Current status of nonsteroidal anti-inflammatory drug (NSAID) use in the United States: risk factors and frequency of complications.  Am J Med 1999. 107 3S-8S; discussion 8S-10S
  • 3 Blum A L, Talley N J, O’Morain C, van Zanten S V, Labenz J, Stolte M, Louw J A, Stubberod A, Theodors A, Sundin M, Bolling-Sternevald E, Junghard O. Lack of effect of treating Helicobacter pylori infection in patients with nonulcer dyspepsia. Omeprazole plus Clarithromycin and Amoxicillin. Effect One Year after Treatment (OCAY) Study Group.  N Engl J Med. 1998;  339 1875-1881
    Search in Google Scholar
  • 4 Chey W D. Accurate diagnosis of Helicobacter pylori. 14C-urea breath test.  Gastroenterol Clin North Am. 2000;  29 895-902
    Search in Google Scholar
  • 5 Cohen H. Peptic ulcer and Helicobacter pylori.  Gastroenterol Clin North Am. 2000;  29 775-789
    Search in Google Scholar
  • 6 Cook D J, Fuller H D, Guyatt G H, Marshall J C, Leasa D, Hall R, Winton T L, Rutledge F, Todd T JR, Roy P, Lacroix J, Griffith L, Willan A, for t he Canadian Critical Care Trials Group. Risk factors for gastrointestinal bleeding in crticially ill patients.  N Engl J Med. 1994;  330 377-381
    Search in Google Scholar
  • 7 Dixon M F, Genta R M, Yardley J H, Correa P. Histological classification of gastritis and Helicobacter pylori infection: an agreement at last? The International Workshop on the Histopathology of Gastritis.  Helicobacter. 1997;  2 S17-24 ((Suppl 1))
    Search in Google Scholar
  • 8 Fendrick A M. The role of economic evaluation in the diagnosis and treatment of Helicobacter pylori infection.  Gastroenterol Clin North Am. 2000;  29 837-851
    Search in Google Scholar
  • 9 Fischbach W, Dragosics B, Kolve-Goebeler M E, Ohmann C, Greiner A, Yang Q, Böhm S, Verreet P, Horstmann O, Busch M, Duhmke E, Müller-Hermelink H K, Wilms K. The German-Austrian Gastrointestinal Lymphoma Study Group . Primary gastric B-cell lymphoma: results of a prospective multicenter study.  Gastroenterology. 2000;  119 1191-1202
    Search in Google Scholar
  • 10 Gisbert J P, Benito L M, Lara S, Vazquez A, Jimenez I, Pajares J M. 13C-urea breath test for the diagnosis of Helicobacter pylori infection: are basal samples necessary?.  Eur J Gastroenterol Hepatol. 2000;  12 1201-1205
    Search in Google Scholar
  • 11 Graham D Y, Lew G M, Klein P D, Evans D G, Evans D J, Saeed Z A. et al . Effect of treatment of Helicobacter pylori infection on the long-term recurrence of gastric and duodenal ulcer.  Ann Intern Med. 1992;  116 705-708
    Search in Google Scholar
  • 12 Graham D Y, Go M F. Helicobacter pylori: current status.  Gastroenterology. 1993;  105 279-282
    Search in Google Scholar
  • 13 Graham D Y, Klein P D. Accurate diagnosis of Helicobacter pylori. 13C-urea breath test.  Gastroenterol Clin North Am. 2000;  29 885-893
    Search in Google Scholar
  • 14 Halm U, Halm F, Thein D, Mohr F W, Mössner J. Helicobacter pylori infection: a risk factor for upper gastrointestinal bleeding after cardiac surgery?.  Crit Care Med. 2000;  28 110-113
    Search in Google Scholar
  • 15 Hawkey C J, Karrasch J A, Szczepanski L, Walker D G, Barkun A, Swannell A J, Yeomans N D. Omeprazole compared with misoprostol for ulcers associated with nonsteroidal antiinflammatory drugs. Omeprazole versus Misoprostol for NSAID-induced Ulcer Management (OMNIUM) Study Group.  N Engl J Med. 1998;  338 727-734
    Search in Google Scholar
  • 16 Ho G Y, Windsor H M. Accurate diagnosis of Helicobacter pylori. Polymerase chain reaction tests.  Gastroenterol Clin North Am. 2000;  29 903-915
    Search in Google Scholar
  • 17 Ho B, Marshall B J. Accurate diagnosis of Helicobacter pylori. Serologic testing.  Gastroenterol Clin North Am. 2000;  29 853-62
    Search in Google Scholar
  • 18 Marshall B J, Warren J R. Unidentified curved bacilli in the stomach of patients with gastritis and peptic ulceration.  Lancet. 1984;  1 1311-1315
    Search in Google Scholar
  • 19 McColl K, Murray L, El-Omar E, Dickson A, El-Nujumi A, Wirz A, Kelman A, Penny C, Knill-Jones R, Hilditch T. Symptomatic benefit from eradicating Helicobacter pylori infection in patients with nonulcer dyspepsia.  N Engl J Med. 1998;  339 1869-1874
    Search in Google Scholar
  • 20 Midolo P, Marshall B J. Accurate diagnosis of Helicobacter pylori. Urease tests.  Gastroenterol Clin North Am. 2000;  29 871-878
    Search in Google Scholar
  • 21 Misiewicz J J, Tytgat G NJ, Goodwin C S. et al .The Sydney System: a new classification of gastritis. Melbourne, Australia: Blackwell Scientific Publications In: Proceedings of the Working Party Report for the Sydney World Congress of Gastroenterology, Sydney, Australia, August 26-31, 1990 1990: 1-10
    Search in Google Scholar
  • 22 Monteiro L, de Mascarel A, Sarrasqueta A M, Bergey B, Barberis C, Talby P, Roux D, Shouler L, Goldfain D, Lamouliatte H, Megraud F. Diagnosis of Helicobacter pylori infection: noninvasive methods compared to invasive methods and evaluation of two new tests.  Am J Gastroenterol. 2001;  96 353-358
    Search in Google Scholar
  • 23 Norton J A, Fraker D L, Alexander H R, Venzon D J, Doppman J L, Serrano J, Goebel S U, Peghini P L, Roy P K, Gibril F, Jensen R T. Surgery to cure the Zollinger-Ellison syndrome.  N Engl J Med. 1999;  341 635-644
    Search in Google Scholar
  • 24 Parsonnet J. The incidence of Helicobacter pylori infection.  Aliment Pharmacol Ther. 1995;  9 45-51 (Suppl 2)
    Search in Google Scholar
  • 25 Perez-Perez G I. Accurate diagnosis of Helicobacter pylori. Culture, including transport.  Gastroenterol Clin North Am. 2000;  29 879-884
    Search in Google Scholar
  • 26 Proye C, Malvaux P, Pattou F, Filoche B, Godchaux J M, Maunoury V, Palazzo L, Huglo D, Lefebvre J, Paris J C. Noninvasive imaging of insulinomas and gastrinomas with endoscopic ulttrasonography and somatostatin receptor scintigraphy.  Surgery. 1998;  124 1134-1143; discussion 1143-1144
    Search in Google Scholar
  • 27 Rosenstock S J, Jorgensen T. Prevalence and incidence of peptic ulcer disease in a Danish County-a prospective cohort study.  Gut. 1995;  36 819-824
    Search in Google Scholar
  • 28 Russmann H, Kempf V A, Koletzko S, Heesemann J, Autenrieth I B. Comparison of fluorescent in situ hybridization and conventional culturing for detection of Helicobacter pylori in gastric biopsy specimens.  J Clin Microbiol. 2001;  39 304-308
    Search in Google Scholar
  • 29 Savarino V, Tracci D, Dulbecco P, Mele M R, Zentilin P, Mansi C, Vigneri S. Negative effect of ranitidine on the results of urea breath test for the diagnosis of Helicobacter pylori.  Am J Gastroenterol. 2001;  96 348-352
    Search in Google Scholar
  • 30 Schenk B E, Kuipers E J, Nelis G F, Bloemena E, Thijs J C, Snel P, Luckers A E, Klinkenberg-Knol E C, Festen H P, Viergever P P, Lindeman J, Meuwissen S G. Effect of Helicobacter pylori eradication on chronic gastritis during omeprazole therapy.  Gut. 2000;  46 615-621
    Search in Google Scholar
  • 31 Schilling D, Jakobs R, Peitz U, Sulliga M, Stolte M, Riemann J F, Labenz J. Diagnostic accuracy of (13)C-Urea Breath Test in the diagnosis of Helicobacter pylori infection in patients with partial gastric resection due to peptic ulcer disease. a prospective multicenter study.  Digestion. 2001;  63 8-13
    Search in Google Scholar
  • 32 Silverstein F E, Graham D Y, Senior J R, Davies H W, Struthers B J, Bittman R M, Geis G S. Misoprostol reduces serious gastrointestinal complications in patients with rheumatoid arthritis receiving nonsteroidal anti-inflammatory drugs. A randomized, double-blind, placebo-controlled trial.  Ann Intern Med. 1995;  123 241-249
    Search in Google Scholar
  • 33 Soll A H. Pathogenesis of peptic ulcer and implications for therapy.  N Engl J Med. 1991;  324 1043-1048
    Search in Google Scholar
  • 34 Sung J, Russell R I, Yeomans N, Chan F K, Chen S, Fock K, Goh K L, Kullavanijaya P, Kimura K, Lau C, Louw J, Sollano J, Triadiafalopulos G, Xiao S, Brooks P. Non-steroidal anti-inflammatory drug toxicity in the upper gastrointestinal tract.  J Gastroenterol Hepatol. 2000;  15 G58-68 (Suppl))
    Search in Google Scholar
  • 35 Talley N J, Vakil N, Ballard E D, Fennerty M B. Absence of benefit of eradicating Helicobacter pylori in patients with nonulcer dyspepsia.  N Engl J Med. 1999;  341 1106-1111
    Search in Google Scholar
  • 36 Vaira D, Menegatti M, Ricci C, Gatta L, Berardi S, Miglioli M. Accurate diagnosis of Helicobacter pylori. Stool tests.  Gastroenterol Clin North Am. 2000;  29 917-923
    Search in Google Scholar
  • 37 Valori R M, Cockel R. Omeprazole for duodenal ulceration in Crohn’s disease.  BMJ. 1990;  300 438-439
    Search in Google Scholar
  • 38 Wilcox C M, Shalek K A, Cotsonis G. Striking prevalence of over-the-counter nonsteroidal anti-inflammatory drug use in patients with upper gastrointestinal hemorrhage.  Arch Intern Med. 1994;  154 42-46
    Search in Google Scholar
  • 39 Wilcox C M, Alexander L N, Cotsonis G A, Clark W S. Nonsteroidal antiinflammatory drugs are associated with both upper and lower gastrointestinal bleeding.  Dig Dis Sci. 1997;  42 990-997
    Search in Google Scholar
  • 40 Yeomans N D, Garas G, Hawkey C J. The nonsteroidal anti-inflammatory drugs controversy.  Gastroenterol Clin North Am. 2000;  29 791-805
    Search in Google Scholar
  • 41 el-Zimaity H M. Accurate diagnosis of Helicobacter pylori with biopsy.  Gastroenterol Clin North Am. 2000;  29 863-869
    Search in Google Scholar

Korrespondenz

Prof. Dr. med. Joachim Mössner

Medizinische Klinik und Poliklinik II Zentrum für Innere Medizin Universität Leipzig

Philipp-Rosenthal-Straße 27

04103 Leipzig

Phone: 0341/9712201

Fax: 0341/9712209

Email: moej@medizin.uni-leipzig.de