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Semin Musculoskelet Radiol 2001; 05(2): 089-094
DOI: 10.1055/s-2001-15658
Copyright © 2001 by Thieme Medical Publishers, Inc., 333 Seventh Avenue, New York, NY 10001, USA. Tel.: +1(212) 584-4662

Pustulotic Arthro-osteitis: Defining the Radiologic Spectrum of the Disease

Kazusa Hyodoh1 , Hideharu Sugimoto2
  • 1Department of Radiology, Sapporo Medical School, Sapporo, Japan
  • 2Department of Radiology, Showa University Fujigaoka Hospital, Yokohama, Japan
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Publication History

Publication Date:
31 December 2001 (online)

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ABSTRACT

Pustulotic arthro-osteitis (PAO) was termed by Sonozaki et al., who discussed the relationship between palmoplantar pustulosis (PPP) and osteoarticular inflammation. Manifestations of PAO are observed in the anterior chest wall, the spine, the pelvis, the sacroiliac joint, and the long bones. Hyperostosis is a radiological feature of PAO; furthermore, anterior chest wall involvement is common. The term SAPHO syndrome (SAPHO being an acronym for synovitis, acne, pustulosis, hypertostosis, and osteitis) has been coined to describe disease that manifests sterile inflammatory bone lesions together with skin eruptions. SAPHO syndrome groups together the following osteo-articular lesions that have been described as separate medical entities: chronic recurrent multifocal osteomyelitis (CRMO), PAO, and arthro-osteitis associated with a follicular occlusive triad. Osseous changes due to psoriasis vulgaris and generalized pustular psoriasis can be radiologically and clinically distinguishable from osseous changes due to PPP, acne, and CRMO as seronegative spondyloarthropathies.

KEYWORD

SAPHO syndrome - pustulotic arthro-osteitis - palmoplantar pustulosis

REFERENCES

  • 1 Sonozaki H, Mitsui H, Miyanaga Y. Clinical features of 53 cases with pustulotic arthro-osteitis.  Ann Rheum Dis . 1981;  40 547-553
    PubMedGoogle Scholar
  • 2 Boutin R D, Resnick D. The SAPHO syndrome: an evolving concept for unifying several idiopathic disorders of bone and skin.  Am J Roentgenol . 1998;  170 585-591
    PubMedGoogle Scholar
  • 3 Sugimoto H, Tamura K, Fujii T. The SAPHO syndrome: defining theradiologic spectrum of disease comprising the syndrome.  Eur Radiol . 1998;  8 800-806
    CrossrefPubMedGoogle Scholar
  • 4 Kahn M F, Kahn M A. The SAPHO syndrome.  Baillieres Clin Rheumatol . 1994;  8 333-362
    CrossrefPubMedGoogle Scholar
  • 5 Toussirot E, Dupond J L, Wendling D. Spondylodiscitis in SAPHO syndrome. A series of eight cases.  Ann Rheum Dis . 1997;  56 52-58
    CrossrefPubMedGoogle Scholar
  • 6 Van Doornum S, Barraclough D, McColl G, Wicks I. SAPHO: rare or just not recognized?.  Semin Arthritis Rheum . 2000;  30 70-77
    CrossrefPubMedGoogle Scholar
  • 7 Nachtigal A, Cardinal E, Bureau N J, Sainte-Marie L G, Milette F. Vertebral involvement in SAPHO syndrome: MRI findings.  Skeletal Radiol . 1999;  28 163-168
    CrossrefPubMedGoogle Scholar