Konservative Therapie der Induratio penis plastica

E. W. Hauck; I. Schroeder-Printzen; W. Weidner

doi:10.1055/s-2001-15946

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Aktuelle Urol 2001; 32(S1): 44-47
DOI: 10.1055/s-2001-15946

KONSERVATIVE THERAPIE

Georg Thieme Verlag Stuttgart · New York

Konservative Therapie der Induratio penis plastica

Conservative Treatment of Induratio Penis PlasticaE. W. Hauck, I. Schroeder-Printzen, W. Weidner

Justus-Liebig-Universität Gießen, Urologische Klinik und Poliklinik

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Publication History

Publication Date:
31 December 2001 (online)

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Zusammenfassung

Dieser Beitrag gibt eine Übersicht über den aktuellen Stand der konservativen medikamentösen Therapie der Induratio penis plastica und schließt die orale und intraläsionale Pharmakaapplikation sowie die Iontophorese, die den transdermalen Wirkstofftransport verstärkt, ein. Nach den Kriterien der „evidence-based medicine” sind nur wenige Substanzen geprüft, nur zwei weisen einen Effekt bei oraler und eine bei intraläsionaler Therapie auf. Die Iontophorese wurde nur unter der Verwendung einer Wirkstoffkombination bislang erfolgreich nach harten Kriterien getestet. Weitere prospektive Studien zur Verifizierung erster Erfolge sind unbedingt erforderlich.

Abstract

This paper reviews the current status on conservative therapy of Peyronie's disease including oral and intralesional drug administration, and iontophoresis that enhances the transdermal drug transport. According to the criteria of „evidence-based medicine” only few substances have been proved, only two oral drugs and one for intralesional administration have been demonstrated to be effective. Iontophoresis has been only investigated under the application of a drug combination according to strict criteria. Further prospective studies for verification of first results urgently required.

Schlüsselwörter

Induratio penis plastica - Konservatie Therapie - Iontophorese

Key words

Peyronie's disease - Conservative Therapy - Iontophoresis

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Prof. Dr. med W Weidner

Justus-Liebig-Universität Gießen
Urologische Klinik und Poliklinik

Klinikstraße 29
35385 Gießen

Phone: Tel.: 0641-9944501

Fax: Fax: 0641-9944509

Email: E-mail: wolfgang.weidner@chiru.med.uni-gießen.de