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J Reconstr Microsurg 2001; 17(5): 363-370
DOI: 10.1055/s-2001-16029
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Copyright © 2001 by Thieme Medical Publishers, Inc., 333 Seventh Avenue, New York, NY 10001, USA. Tel.: +1(212) 584-4662

Nerve Conduit Using Fascia-Wrapped Fibrocollagenous Tube

Kazumi Watanabe, Taku Tsukagoshi, Masayoshi Kuroda, Yoshiaki Hosaka
  • Department of Plastic and Reconstructive Surgery, Showa University, Tokyo, Japan
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Publication History

Publication Date:
31 December 2001 (online)

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ABSTRACT

The purpose of this study was to evaluate the application of autogenous fascia as a framework of a fibrocollagen tube for a nerve conduit in Japanese white rabbits. The fascia was wrapped with a double layer around a silicone rod 3.0 mm in diameter. After the implantation of the fascia-wrapped silicone rod into a subcutaneous pocket for 2 weeks, a 3.0 × 30-mm fascia-wrapped fibrocollagen (FFC) tube was prepared. With microvascular techniques, the tube was interposed into a right sciatic nerve gap which was 25 mm long.

The results of nerve regeneration in the FFC tube group, in particular, the formation of epineurium, were able to stand comparison with the results of a control group under both histologic and electron micrographic examination.

KEYWORD

Autogenous fascia - fibrocollagen tube - nerve conduit - nerve regeneration

REFERENCES

  • 1 Millesi H. Indications and techniques of nerve grafting. In: Gelbermenn RH (ed): Opperative Nerve Repair and Reconstruction Philadelphia: JB Lippincott 1991: 525
    Search in Google Scholar
  • 2 Frykman G K. The quest for better recovery from peripheral nerve injury: current status of nerve regeneration research.  J Hand Ther . 1993;  6 83
    PubMedSearch in Google Scholar
  • 3 Makitie A, Paavolainen M. Facial nerve palsy as initial symptom of parotid gland cancer.  Duodenum . 1994;  110 2227
    PubMedSearch in Google Scholar
  • 4 Jaaskelainen J, Pyykko I, Blomstedtt G. Functional results of facial nerve suture after removal of acoustic neurinoma: analysis of 25 cases.  Neurosurgery . 1990;  27 408
    PubMedSearch in Google Scholar
  • 5 Beazley W C, Milek M A, Reiss B H. Results of nerve grafting in severe soft tissue injuries.  Clin Orthoped Rel Res . 1984;  188 208
    PubMedSearch in Google Scholar
  • 6 Young V I, Wray C R, Weeks P M. The results of nerve grafting in the wrist and hand.  Ann Plast Surg . 1980;  5 212
    CrossrefPubMedSearch in Google Scholar
  • 7 Dellon A L. Results of nerve repair in the hand. In: Evaluation of Sensibility and Re-education of Sensation in the Hand Baltimore: Williams and Wilkins 1981: 193
    Search in Google Scholar
  • 8 Lundborg G, Rosen B, Dahlin L. Tubular versus conventional repair of median and ulnar nerves in the human forearm: early results from a prospective, randomised, clinical study.  J Hand Surg . 1997;  22A 99
    PubMedSearch in Google Scholar
  • 9 Norris R W, Glasby M A, Gattuso J M, Bowden R E. Peripheral nerve repair in humans using muscle autografts: a new technique.  J Bone Joint Surg . 1988;  70B 530
    PubMedSearch in Google Scholar
  • 10 Tsukagoshi T, Yenidunya M O, Sasaki E. Experimental vascular graft using small-caliber fascia-wrapped fibrocollagenous tube: short-term evaluation.  J Reconstr Microsurg . 1999;  15 127
    PubMedSearch in Google Scholar
  • 11 Health C A, Rutkowski G E. The development of bioartificial nerve grafts for peripheral-nerve regeneration.  Trends in Biotechnology . 1998;  16 163
    CrossrefPubMedSearch in Google Scholar
  • 12 Li S T, Archibald S J, Krarup C. Peripheral nerve repair with collagen conduits.  Clin Materials . 1992;  9 195
    CrossrefPubMedSearch in Google Scholar
  • 13 Kline D G, Hayes G J. The use of a resorbable wrapper for peripheral nerve repair.  J Neurosurg . 1964;  21 737
    PubMedSearch in Google Scholar
  • 14 Suematsu N, Atsuta Y, Hirayama T. Vein graft for repair of peripheral nerve gap.  J Reconstr Microsurg . 1988;  4 313-318
    PubMedSearch in Google Scholar
  • 15 Lundborg G, Hansson H A. Nerve regeneration through preformed pseudosynovial tubes: a preliminary report of a new experimental model for studying the regeneration and reorganization capacity of peripheral nerve tissue.  J Hand Surg . 1980;  5A 35
    PubMedSearch in Google Scholar
  • 16 Glasby M A, Gattuso J M, Huang C LH. Recovery of peripheral nerves after surgical repair with treated muscle grafts I: physiological assessment.  Neuro Orthopedics . 1988;  5 59
    PubMedSearch in Google Scholar
  • 17 Young B L, Begovac P, Stuart D G, Goslow Jr E G. An effective sleeving technique in nerve repair.  J Neurosci Methods . 1984;  10 51
    CrossrefPubMedSearch in Google Scholar
  • 18 Cragg B G, Thomas P K. The conduction velocity of regenerated peripheral nerve fibers.  J Physiol . 1964;  171 164
    PubMedSearch in Google Scholar
  • 19 Richards F M, Knowles J R. Glutaraldehyde as a protein cross linking agent.  J Mol Biol . 1968;  37 231
    CrossrefPubMedSearch in Google Scholar
  • 20 Perloff L J, Rechard C R, Rowlands D T, Barker C F. The venous homograft.  Ann Surg . 1977;  10 77
    PubMedSearch in Google Scholar
  • 21 Agius E, Cochard P. Compression of neurite outgrowth induced by intact and injured sciatic nerve: a confocal and functional analysis.  J Neurosci . 1998;  18 328
    PubMedSearch in Google Scholar
  • 22 Thomas P K, Jones D G. The cellular response to nerve injury. II. Regeneration of the perineurium after nerve section.  J Anat . 1967;  101 45
    PubMedSearch in Google Scholar
  • 23 Thomas P K, Bhagat S. The effect of extraction of the intrafascicular contents of peripheral nerve trunks on perineurial structure.  Acta Neuropathol (Berl) . 1978;  43 135
    CrossrefPubMedSearch in Google Scholar
  • 24 Torigoe K. Stimulation and inhibition mechanisms in peripheral nerve regeneration.  Kaibougaku Zasshi . 1999;  74 363
    PubMedSearch in Google Scholar