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Synthesis 2001(10): 1479-1482
DOI: 10.1055/s-2001-16077
DOI: 10.1055/s-2001-16077
PAPER
© Georg Thieme Verlag Stuttgart · New York
A New and Convenient Synthesis of 1-Aryl-2-dimethylaminoethanols
Weitere Informationen
Received
8 February 2001
Publikationsdatum:
23. September 2004 (online)
Publikationsverlauf
Publikationsdatum:
23. September 2004 (online)
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Abstract
An efficient two-step synthesis of 1-aryl-2-dimethylaminoethanols 4 is described, consisting of oxazolidine 3 generation from the cycloaddition of an azomethine ylide to an aldehyde, followed by reductive ring-opening.
Key words
aldehydes - amino alcohols - cycloadditions
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