The regiospecific one-pot synthesis of a novel series of 6-alkyl(aryl)-2-[3-alkyl(aryl)-5-trifluoromethyl-5-hydroxy-4,5-dihydro-1H-pyrazol-l-yl]-4-trifluoromethylpyrimidines 2 and 6-alkyl(aryl)-2-[3-alkyl(aryl)-5-trifluoromethyl-1H-pyrazol-l-yl]- 4-trifluoromethylpyrimidines 3 from 4-alkyl(aryl)-1,1,1-trifluoro-4-methoxyalk-3-en-2-ones 1 and aminoguanidine bicarbonate is reported.
pyrimidines - pyrazoles - 2-(pyrazolyl)pyrimidines - trifluoromethyl vinyl ketones
