Planta Med 2001; 67(6): 570-572
DOI: 10.1055/s-2001-16481
Letter

© Georg Thieme Verlag Stuttgart · New York

Coronin from Roots of Annona muricata, a Putative Intermediate in Acetogenin Biosynthesis (1)

Christophe Gleye, Blandine Akendengue, Alain Laurens, Reynald Hocquemiller
  • Laboratoire de Pharmacognosie, UPRES-A CNRS 8076 (BioCIS), Faculté de Pharmacie de l’Université Paris XI, France
Further Information

Publication History

August 4, 2000

December 3, 2000

Publication Date:
17 August 2001 (online)

Abstract

A novel acetogenin, coronin, was isolated from the roots of Annona muricata L. The structure was elucidated by a combination of chemical and spectral methods including MS and NMR measurements. Coronin is probably an intermediate in the biosynthetic pathway of bis-tetrahydrofuran acetogenins, and is proposed as a biogenetic precursor of neoannonin-B.

References

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Prof. Alain Laurens

Laboratoire de Pharmacognosie

UPRES-A CNRS 8076 (BioCIS)

Faculté de Pharmacie

92296 Châtenay-Malabry

France

Email: alain.laurens@cep.u-psud.fr

Fax: +33-1-4683-5399