Abstract
New terdentate facially binding ligands based on the 2-pyridinyl-α-ethanol skeleton were prepared as the racemates. Reaction with the enantiomerically pure (-)-(1S,4R)-camphanoyl chloride gave diastereomeric camphanic esters. The pure diastereomers were accessible by separating the diastereomeric esters with medium-pressure silica gel chromatography or fractional crystallization. X-ray structure analysis of the pure camphanic esters established the absolute configurations of the 2-pyridinyl-α-alcohols. The enantiomerically pure alcohols were obtained after saponification of the diastereomerically pure esters.
Key words
facial coordination - terdentate ligands - chiral 2-pyridinyl-α-alcohols - absolute configuration
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