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Synlett 2001; 2001(9): 1443-1445
DOI: 10.1055/s-2001-16802
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Biphenylphosphine-Palladium(II) Complexes-Catalyzed Friedel-Crafts Reaction for the Synthesis of α-Amino and α-Hydroxy Indolylacetates and Diindolylacetates

Jian Hao* , Sonia Taktak, Kousuke Aikawa, Yukinori Yusa, Manabu Hatano, Koichi Mikami
  • *Department of Applied Chemistry, Tokyo Institute of Technology, Tokyo 152-8552, Japan; Fax + 81-3-5734-2776; E-mail: kmikami@o.cc.titech.ac.jp
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Publication Date:
28 August 2001 (online)

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Biphenylphosphine-palladium(II) complexes-catalyzed Friedel-Crafts reaction of N-methylindol with imino and carbonyl compounds afforded α-amino and α-hydroxy substituted indolyl-acetates and diindolylacetates in good yields.

biphenylphosphine - palladium complexes - Friedel-Crafts reaction - indoles