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Dtsch Med Wochenschr 2001; 126(38): 1053-1057
DOI: 10.1055/s-2001-17312
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© Georg Thieme Verlag Stuttgart · New York

Therapeutische Neoangiogenese

Alternative oder adjuvante Option bei der Behandlung fortgeschrittener koronarer und peripherer ischämischer GefäßerkrankungenTherapeutic neo-angiogenesis: alternative or adjuvant option in the treatment of advanced coronary and peripheral ischaemic vascular diseaseM. G. Engelmann, S. Nikol
  • Medizinische Klinik I (Direktor: Prof. Dr. G. Steinbeck), Ludwig-Maximilians-Universität, Klinikum Großhadern, München
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Publication History

Publication Date:
20 September 2001 (online)

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Das therapeutische Potenzial angiogener Wachstumsfaktoren ist seit mehreren Jahrzehnten bekannt [10]. In zahlreichen Untersuchungen konnte für mehrere Gefäßwachstumsfaktoren die Fähigkeit der vermehrten Kapillar- und Kollateralgefäßbildung in Tiermodellen mit myokardialer oder Beinarterienischämie nachgewiesen werden [12]. Diese innovative Form der Behandlung ischämischer Erkrankungen wird als »therapeutische Angiogenese« bezeichnet und könnte als adjuvante oder alternative Behandlung bei fortgeschrittenen Stadien der ischämischen Herzerkrankung oder der peripheren arteriellen Verschlusskrankheit eingesetzt werden.

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Korrespondenz

Priv.-Doz. Dr. med. Sigrid Nikol

Medizinische Klinik I Klinikum Großhadern

Marchioninistraße 15

81377 München

Phone: 089/7095 0

Fax: 089/7095 6166

Email: s-nikol@gmx.de