Flat and depressed cancers of the colon have now been recognized in several centers throughout the world. We report here a case of a 0.8-mm depressed adenoma with high-grade dysplasia in a 70-year-old man. We believe this to be the smallest adenoma ever reported, and unusually (for a small lesion) it was positive for the K-ras mutation.
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G. Naylor
Dept. of Gastroenterology
John Hunter Hospital
Newcastle, New South Wales 2300
Australia
Fax: + 61-249-213998
eMail: gregnaylor@fsmail.net
