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DOI: 10.1055/s-2001-17490
Dokumentierte Infektionen bei Neutropenie - Empfehlungen zu Diagnostik und Therapie
Arbeitsgemeinschaft Infektionen in der Hämatologie und Onkologie - Fachgruppe der Deutschen Gesellschaft für Hämatologie und OnkologieDocumented infections with neutropenia: therapeutic and diagnostic recommendationsPublication History
Publication Date:
27 September 2001 (online)
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Vorbemerkung
Standardempfehlungen und Leitlinien der »Arbeitsgemeinschaft Infektionen in der Hämatologie und Onkologie« der Deutschen Gesellschaft für Hämatologie und Onkologie (DGHO) zu Diagnostik und Therapie von Fieber unklarer Genese [23], Pilzinfektionen [3], Infektionen nach Hochdosistherapie und autologer Stammzelltransplantation [28], Sepsis in der Neutropenie [37], Venenkatheter-assoziierten Infektionen [11], Lungeninfiltraten bei neutropenischen Patienten [27] und zur Infektionsprophylaxe [20] wurden bereits in der DMW publiziert.
Literatur
- 1 Anand A, Glatt A E. Clostridium difficile infection associated with antineoplastic chemotherapy: a review. Clin Infect Dis. 1993; 17 109-113
- 2 Bochud P Y, Calandra T, Francioli P. Bacteremia due to viridans streptococci in neutropenic patients: a review. Am J Med. 1994; 97 256-264
- 3 Böhme A, Karthaus M, Einsele H. et al . Diagnostik systemischer Pilzinfektionen in der Hämatologie. Dtsch Med Wochenschr. 1999; 124 S24-30
- 4 Caplan E S, Hoyt N J. Nosocomial sinusitis. JAMA. 1982; 247 639-641
- 5 Chirletti P, Barillari P, Sammartino P. et al . The surgical choice in neutropenic patients with hematological disorders and acute abdominal complications. Leuk Lymphoma. 1993; 9 237-241
- 6 Denning D W, Evans E G, Kibbler C C. et al . Guidelines for the investigation of invasive fungal infections in haematological malignancy and solid organ transplantation. Eur J Clin Microbiol Infect Dis. 1997; 16 424-436
- 7 deShazo R D, Chapin K, Swain R E. Fungal sinusitis. N Engl J Med. 1997; 337 254-259
- 8 Drakos P E, Nagler A, Or R. et al . Invasive fungal sinusitis in patients undergoing bone marrow transplantation. Bone Marrow Transplant. 1993; 12 203-208
- 9 Elting L S, Rubenstein E B, Rolston K V. et al . Outcomes of bacteremia in patients with cancer and neutropenia: observations from two decades of epidemiological and clinical trials. Clin Infect Dis. 1997; 25 247-259
- 10 Escande M C, Herbrecht R. Prospective study of bacteraemia in cancer patients. Results of a French multicentre study. Support Care Cancer. 1998; 6 273-280
- 11 Fätkenheuer G, Buchheidt D, Fuhr H G. et al . Venenkatheter-assoziierte Infektionen bei Patienten mit Neutropenie. Dtsch Med Wochenschr. 2001; 126 89-95
- 12 Gerding D N, Johnson S, Peterson L R, Mulligan M E, Silva J . Society for Healthcare and Epidemiology of America: position paper on Clostridium difficile-associated diarrhea and colitis. Infect Control Hosp Epidemiol. 1995; 16 459-477
- 13 Gillespie M B, O’Malley B WJ, Francis H W. An approach to fulminant invasive fungal rhinosinusitis in the immunocompromised host. Arch Otolaryngol Head Neck Surg. 1998; 124 520-526
- 14 Guppy K H, Thomas C, Thomas K, Anderson D. Cerebral fungal infections in the immunocompromised host: a literature review and a new pathogen-Chaetomium atrobrunneum: case report. Neurosurgery. 1998; 43 1463-1469
- 15 Hagensee M E, Bauwens J E, Kjos B, Bowden R A. Brain abscess following marrow transplantation: experience at the Fred Hutchinson Cancer Research Center, 1984 - 1992. Clin Infect Dis. 1994; 19 402-408
- 16 Hughes W T, Armstrong D, Bodey G P, Brown A E, Edwards J E, Feld R, Pizzo P, Rolston K V, Shenep J L, Young L S. 1997 guidelines for the use of antimicrobial agents in neutropenic patients with unexplained fever. Infectious Diseases Society of America. Clin Infect Dis. 1997; 25 551-573
- 17 Iino T, Gondo H, Ohno Y. et al . Successful foscarnet therapy for mucocutaneous infection with Herpes simplex virus in a recipient after unrelated bone marrow transplantation. Bone Marrow Transplant. 1996; 18 1185-1188
- 18 Jacobs L G. Fungal urinary tract infections in the elderly: treatment guidelines. Drugs Aging. 1996; 8 89-96
- 19 Kennedy C A, Adams G L, Neglia J P, Giebink G S. Impact of surgical treatment on paranasal fungal infections in bone marrow transplant patients. Otolaryngol Head Neck Surg. 1997; 116 610-616
- 20 Kern W V, Beyer J, Böhme A. et al . Infektionsprophylaxe bei neutropenischen Patienten. Dtsch Med Wochenschr. 2000; 125 1582-1588
- 21 Kyne L, Warny M, Qamar A, Kelly C P. Asymptomatic carriage of Clostridium difficile and serum levels of IgG antibody against toxin A. N Engl J Med. 2000; 342 390-397
- 22 Lazarus H M, Belanger R, Candoni A, Aoun M, Jurewicz R, Marks L. Intravenous penciclovir for treatment of Herpes simplex infections in immunocompromised patients: results of a multicenter, acyclovir-controlled trial. Antimicrob Agents Chemother. 1999; 43 1192-1197
- 23 Link H, Blumenstengel K, Böhme A. et al . Antimikrobielle Therapie von unerklärtem Fieber bei Neutropenie. Dtsch Med Wochenschr. 1999; 124 S3-S8
- 24 Link H, Maschmeyer G, Meyer P. et al . Interventional antimicrobial therapy in febrile neutropenic patients. Ann Hematol. 1994; 69 231-243
- 25 Loyer E M, DuBrow R A, David C L, Coan J D, Eftekhari F. Imaging of superficial soft-tissue infections: sonographic findings in cases of cellulitis and abscess. Am J Roentgenol. 1996; 166 149-152
- 26 Maschmeyer G. Interventional antimicrobial therapy in febrile neutropenic patients. Diagn Microbiol Infect Dis. 1999; 34 205-212
- 27 Maschmeyer G, Beinert T, Buchheidt D, Einsele H, Holler E. Diagnostik und Therapie von Lungeninfiltraten bei febrilen neutropenischen Patienten. Dtsch Med Wochenschr. 1999; 124 S18-S23
- 28 Maschmeyer G, Hertenstein B, Glass B, Schiel X. Interventionelle antimikrobielle Therapie febriler Komplikationen nach Hochdosistherapie und autologer Stammzelltransplantation. Dtsch Med Wochenschr. 1999; 124 S9-13
- 29 Maschmeyer G, Hiddemann W, Link H. et al . Management of infections during intensive treatment of hematologic malignancies. Ann Hematol. 1997; 75 9-16
- 30 Matsumoto T, Takahashi K, Tanaka M, Kumazawa J. Infectious complications of combination anticancer chemotherapy for urogenital cancers. Int Urol Nephrol. 1999; 31 7-14
- 31 McFarland L V, Mulligan M E, Kwok R Y, Stamm W E. Nosocomial acquisition of Clostridium difficile infection. N Engl J Med. 1989; 320 204-210
- 32 Montalban C, Patier J L, Calleja J L, Perales J, Serrano M, Bellas C. Neutropenic enterocolitis during treatment of lymphoproliferative neoplasms. Med Clin (Barc). 1989; 93 649-652
- 33 Morgan M A, Wilson W R, Neel H B, Roberts G D. Fungal sinusitis in healthy and immunocompromised individuals. Am J Clin Pathol. 1984; 82 597-601
- 34 Nadel D M, Lanza D C, Kennedy D W. Endoscopically guided cultures in chronic sinusitis. Am J Rhinol. 1998; 12 233-241
- 35 Nguyen-Van-Tam S E, Nguyen-Van-Tam J S, Myint S, Pearson J C. Risk factors for hospital-acquired urinary tract infection in a large English teaching hospital: a case-control study. Infection. 1999; 27 192-197
- 36 Nielsen H, Daugaard G, Tvede M, Bruun B. High prevalence of Clostridium difficile diarrhoea during intensive chemotherapy for disseminated germ cell cancer. Br J Cancer. 1992; 66 666-667
- 37 Ostermann H, Derigs H G, Heussel G. et al . Sepsis in Neutropenie. Dtsch Med Wochenschr. 1999; 124 S14-S17
- 38 Patchell R A, Posner J B. Neurologic complications of systemic cancer. Neurol Clin. 1985; 3 729-750
- 39 Peterson K L, Wang M, Canalis R F, Abemayor E. Rhinocerebral mucormycosis: evolution of the disease and treatment options. Laryngoscope. 1997; 107 855-862
- 40 Pizzo P A, Ladisch S, Ribichaud K. Treatment of gram-positive septicemia in cancer patients. Cancer. 1980; 45 206-207
- 41 Shamberger R C, Weinstein H J, Delorey M J, Levey R H. The medical and surgical management of typhlitis in children with acute nonlymphocytic (myelogenous) leukemia. Cancer. 1986; 57 603-609
- 42 Shim J K, Johnson S, Samore M H, Bliss D Z, Gerding D N. Primary symptomless colonisation by Clostridium difficile and decreased risk of subsequent diarrhoea. Lancet. 1998; 351 633-636
- 43 Teasley D G, Gerding D N, Olson M M. et al . Prospective randomised trial of metronidazole versus vancomycin for Clostridium-difficile-associated diarrhoea and colitis. Lancet. 1983; 2 1043-1046
- 44 von Herbay A, Möller P, Ludwig W, Otto H F. Neutropenische Enterocolitis. Dtsch Med Wochenschr. 1989; 114 293-297
- 45 Wade D S, Nava H R, Douglass H OJ. Neutropenic enterocolitis. Clinical diagnosis and treatment. Cancer. 1992; 69 17-23
- 46 Yuen K Y, Woo P C, Liang R H. et al . Clinical significance of alimentary tract microbes in bone marrow transplant recipients. Diagn Microbiol Infect Dis. 1998; 30 75-81
Korrespondenz
Dr. med. Dieter Buchheidt
III. Medizinische Klinik Universitätsklinikum
Mannheim, Ruprecht-Karls-Universität Heidelberg
Wiesbadener Straße 7-11
68305 Mannheim
Phone: 0621/383.4110
Fax: 0621/383.4201
Email: dieter.buchheidt@urz.uni-heidelberg.de