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Synthesis 2001(14): 2165-2169
DOI: 10.1055/s-2001-18068
DOI: 10.1055/s-2001-18068
PAPER
© Georg Thieme Verlag Stuttgart · New York
InCl3-Catalysed Conjugate Addition of Indoles with Electron-Deficient Olefins [1]
Weitere Informationen
Publikationsverlauf
Received
18 April 2001
Publikationsdatum:
09. August 2004 (online)


Abstract
Indole and 2-methylindole undergo conjugate addition with electron-deficient olefins in the presence of a catalytic amount of InCl3 at ambient temperature to afford the corresponding Michael adducts in excellent yields with high selectivity.
Key words
indium trichloride - indole - α,β-unsaturated compounds - addition reactions
IICT communication No. 4745.