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Synlett 2001; 2001(11): 1755-1758
DOI: 10.1055/s-2001-18103
DOI: 10.1055/s-2001-18103
letter
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The Studies of the Intramolecular C-F-H-N Hydrogen Bonding Using Covalently-Linked Base Pair Models of F and A
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Publication History
Publication Date:
29 October 2001 (online)
Both 1H NMR and X-ray studies revealed that C-F-H-N intramolecular hydrogen bonding is not observed even in covalently-linked base pair models of F and A. These results strongly support the Kool's hypothesis.
nucleobases - intramolecular - hydrogen bonding - fluorine - DNA