Planta Med 2001; 67(8): 732-736
DOI: 10.1055/s-2001-18338
Original Paper
Natural Product Chemistry
© Georg Thieme Verlag Stuttgart · New York

Isolation from Cussonia barteri of 1′-O-Chlorogenoylchlorogenic Acid and 1′-O-Chlorogenoylneochlorogenic Acid, a New Type of Quinic Acid Esters

S. Papajewski1 , B. Vogler1 , J. Conrad1 , I. Klaiber1 , G. Roos1 , C. U. Walter1 , R. Süßmuth2 , W. Kraus1,*
  • 1 Institut für Chemie, Lehrstuhl für Organische Chemie, Universität Hohenheim, Stuttgart, Germany
  • 2 Institut für Mikrobiologie, Universität Hohenheim, Stuttgart, Germany
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Publikationsverlauf

September 15, 2000

December 15, 2000

Publikationsdatum:
09. November 2001 (online)

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Abstract

1′-O-Chlorogenoylchlorogenic acid and 1′-O-chlorogenoylneochlorogenic acid, a new type of quinic acid esters, have been isolated, in addition to six known quinic acid esters, rutin, and a mixture of saponins, from the methanol extract of Cussonia barteri Seemann (Araliaceae) leaves collected in Cameroon. Structure determination was achieved by NMR, mass, IR, and UV spectroscopy. All compounds were tested for inhibitory activity on 5-lipoxygenase and cyclooxygenase-1, for antimicrobial activity against Bacillus subtilis, Pseudomonas fluorescens, and Cladosporium cucumerinum, and for haemolytic actvity.

References

Prof. Dr. Wolfgang Kraus

Institut für Chemie

Universität Hohenheim

Garbenstr. 30

70593 Stuttgart

Germany

eMail: kraus130@uni-hohenheim.de

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