The recognition that hypertriglyceridemia is associated with multiple alterations
of other lipoproteins that are potentially atherogenic has expanded the picture of
diabetic dyslipidemia. Elevation of large VLDL1 particles initiate a sequency of events
that results in generation of atherogenic lipoproteins including remnants and small
dense LDL. This abnormality is also associated with the lowering of HDL cholesterol.
The clinical implication is that the concentration of plasma triglycerides should
be maintained as low as possible to avoid these deleterious consequences of hypertriglyceridemia.
Type 2 diabetes - lipoproteins - apoproteins - small dense LDL
