Planta Med 2001; 67(9): 863-864
DOI: 10.1055/s-2001-18846
Letter

© Georg Thieme Verlag Stuttgart · New York

Absorption of Dodeca-2E,4E,8Z,10E/Z-tetraenoic Acid Isobutylamides after Oral Application of Echinacea purpurea Tincture[1]

Birgit Dietz1 , Jörg Heilmann2 , Rudolf Bauer1
  • 1 Institute of Pharmaceutical Biology, Düsseldorf, Germany
  • 2 ETH Zürich, Institute of Pharmaceutical Sciences, Zürich, Switzerland
Further Information

Publication History

December 8, 2000

March 10, 2001

Publication Date:
06 December 2001 (online)

Abstract

Alkamides are suspected to contribute to the activity of Echinacea preparations. In preliminary experiments a quantification method for dodeca-2E,4E,8Z,10E/Z-tetraenoic acid isobutylamides in human blood has been developed by which it was possible to detect dodeca-2E,4E,8Z,10E/Z-tetraenoic acid isobutylamides in human blood after oral application of Echinacea purpurea mother tincture.

1 This work is part of the Ph.D. thesis of B. Dietz

References

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  • 6 Clifford L J, Nair M G, Rana J, Koedam J, Zemaitis D. Anti-inflammatory and antioxidant activities of Echinacea purpurea and Echinacea angustifolia root extracts. 46th Annual Congress of the Society for Medicinal Plant Research 1999: Book of Abstracts, No.665
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1 This work is part of the Ph.D. thesis of B. Dietz

Prof. Dr. Rudolf Bauer

Institut für Pharmazeutische Biologie

Heinrich-Heine-Universität Düsseldorf

Universitätsstraße 1

40225 Düsseldorf

Germany

Email: Rudolf.Bauer@uni-duesseldorf.de

Fax: +49 211-8111745