Therapie von Pilzinfektionen in der Hämatologie und Onkologie

A. Böhme; M. Ruhnke; M. Karthaus; H. Einsele; S. Guth; G. Heußel; C. P. Heußel; C. Junghanss; W. V. Kern; T. Kubin; O. Sezer; G. Silling; T. Südhoff; H. Szelényi; A. J. Ullmann

doi:10.1055/s-2001-18975

DMW - Deutsche Medizinische Wochenschrift, Table of Contents

Dtsch Med Wochenschr 2001; 126(50): 1440-1447
DOI: 10.1055/s-2001-18975

Fachgremien & Konsensuskonferenzen

Therapie von Pilzinfektionen in der Hämatologie und Onkologie

Leitlinien der Arbeitsgemeinschaft Infektionen in der Hämatologie und Onkologie (AGIHO) der Deutschen Gesellschaft für Hämatologie und Onkologie (DGHO)Treatment of fungal infections in haematology and oncology. Guidelines of the Working Party on Infections in Haematology and Oncology (AGIHO) of the German Society for Haematology and Oncology (DGHO)A. Böhme¹ , M. Ruhnke ² , M. Karthaus³ , H. Einsele⁴ , S. Guth ⁵ , G. Heußel⁶ , C. P. Heußel⁷ , C. Junghanss ⁸ , W. V. Kern⁹ , T. Kubin¹⁰ , O. Sezer ² , G. Silling¹¹ , T. Südhoff¹² , H. Szelényi ¹³ , A. J. Ullmann⁶

¹Med. Klin. III (Direktor: D. Hoelzer), J. W. Goethe-Universität Frankfurt
²Abt. Innere Med., Schwerp. Hämatologie/Onkologie (Direktor: K. Possinger), Charité, Campus Mitte der Humboldt-Universität zu Berlin
³Med. Klinik II, Ev. Johannes-Krankenhaus (Leiter: M. Karthaus) Bielefeld
⁴Med. Klinik u. Poliklinik, Abt. und Lehrstuhl II (Direktor: L. Kanz), Univ.klinikum Tübingen
⁵Klinik u. Poliklinik für Herz-, Thorax- und Gefäßchirurgie (Direktor: H. Oelert), Johannes Gutenberg-Universität Mainz
⁶III. Med. Klinik u. Poliklinik (Direktor: Ch. Huber), Johannes Gutenberg-Universität Mainz
⁷Klinik u. Poliklinik für Radiologie (Direktor: M. Thelen), Johannes Gutenberg-Universität, Mainz
⁸Abt. Hämatologie/Onkologie (Direktor: M. Freund), Univ.klinikum Rostock
⁹Innere Med. III, (Direktor: H. Döhner), Univ. Ulm
¹⁰II. Medizin, Hämatologie/Onkologie/Infektionskrankheiten (Direktor: J. Th. Fischer), Städt. Klinikum Karlsruhe
¹¹Med. Klinik A, Hämatologie/Onkologie, KMT-Zentrum (Direktor: W.E. Berdel), Westfälische-Wilhelms-Universität Münster
¹²Medizinische Klinik (Direktor: W. Schmiegel) der Ruhr-Universität, Knappschaftskrankenhaus Bochum
¹³Med. Klinik III, Schwerpunkt Hämatologie, Onkologie u. Transfusionsmedizin (Direktor: E. Thiel), Univ.klinikum Benjamin Franklin Berlin

Abstract

The Infectious Diseases Working Party of the German Society of Hematology and Oncology presents their guidelines for the treatment of fungal infections in patients with hematological and oncological malignancies. These guidelines are evidence-based considering study results, case reports and expert opinions using the evidence criteria of the Infectious Diseases Society of America (IDSA). They offer actual standards and open questions in the treatment of oropharyngeal and esophageal candidosis, invasive candida infections, cryptococcosis, aspergilloses and mucormycoses. Recommendations for the use and handling of amphotericin B, amphotericin B lipid formulations, azoles and combination therapy are given as well as informations about investigational drugs. Surgical procedures, treatment with hematopoietic growth factors and innovative approaches such as granulocyte transfusion are discussed.

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Korrespondenz

PD Dr. Angelika Böhme*

Med. Klin III, J.W. Goethe-Universität

Theodor-Stern-Kai 7

60590 Frankfurt

Phone: 069/63015194

Fax: 069/63017326

Email: A. boehme@em.uni-frankfurt.de

*gefördert vom BMBF Kompetenznetz Akute und chronische Leukämien