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Synthesis 2002(1): 0034-0038
DOI: 10.1055/s-2002-19290
DOI: 10.1055/s-2002-19290
PAPER
© Georg Thieme Verlag Stuttgart · New York
A Simple Route to N-ω-Chloroalkylisatins from Cyclic t-Anilines, Oxalyl Chloride and DABCO
Weitere Informationen
Received
7 September 2001
Publikationsdatum:
04. August 2004 (online)
Publikationsverlauf
Publikationsdatum:
04. August 2004 (online)
Abstract
para-Substituted N-phenylpyrrolidines, -piperidines, -perhydroazepines and -morpholines react with oxalyl chloride and DABCO to give the pharmaceutically useful intermediates, N-ω-haloalkylisatins, under mild conditions and generally good yields.
Key words
cyclic t-anilines - oxalyl chloride - DABCO - N-ω-haloalkylisatins
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