Planta Med 2002; 68(1): 41-44
DOI: 10.1055/s-2002-19867
Original Paper
Natural Product Chemistry
© Georg Thieme Verlag Stuttgart · New York

New and Antifungal Xanthones from Calophyllum caledonicum

Cécile Morel1 , Denis Séraphin1 , Agnès Teyrouz2 , Gérald Larcher2 , Jean-Philippe Bouchara2 , Marc Litaudon3 , Pascal Richomme1 , Jean Bruneton1
  • 1SONAS, UFR des Sciences Pharmaceutiques et Ingénierie de la santé, 16, Bd Daviers, Angers, France
  • 2Groupe d’Etude des Interactions Hôte-Parasite, Laboratoire de Parasitologie-Mycologie, Centre Hospitalier Universitaire, Angers, France
  • 3ICSN-CNRS, Gif-sur-Yvette, France
Further Information

Publication History

February 23, 2001

March 31, 2001

Publication Date:
31 January 2002 (online)

Abstract

Two new xanthones, namely caledonixanthones E (1) and F (2), were isolated from the stem bark of Calophyllum caledonicum (Guttiferae). The structural elucidation of these compounds was mainly established on the basis of 1D, 2D NMR and HRMS spectroscopic analysis. Among the isolated compounds, eight other known xanthones were also identified in the course of this phytochemical study. In addition to this report, a preliminary evaluation of the antifungal properties of these polyphenolic compounds against Aspergillus fumigatus and Candida albicans is presented.

References

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Prof. Dr. Pascal Richomme

Laboratoire de Pharmacognosie

UFR Sciences Pharmaceutiques

16, Bd Daviers

49100 Angers

France

Email: pascal.richomme@univ-angers.fr.

Fax: +33 2-41-48-67-33