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J Reconstr Microsurg 2002; 18(2): 111-114
DOI: 10.1055/s-2002-19890
Copyright © 2002 by Thieme Medical Publishers, Inc., 333 Seventh Avenue, New York, NY 10001, USA. Tel.: +1(212) 584-4662

Assessment of the Patency of Microvascular Venous Anastomosis

Kenneth C.W. Hui1 , Feng Zhang2 , William W. Shaw3 , Andrew Taylor2 , Ewa Komorowska-Timek2 , William C. Lineaweaver2
  • 1Private practice, Hong Kong
  • 2Division of Plastic Surgery, University of Mississippi Medical Center, Jackson, MS
  • 3Division of Plastic and Reconstructive Surgery, University of California at Los Angeles, CA
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Publication History

Publication Date:
31 January 2002 (online)

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ABSTRACT

There is an absence of data on the timing of occlusion of vessels after anastomosis, and on the possible subsequent reopening (recanalization) of these vessels. This lack of information may be an important factor in the wide discrepancies found among reported patency rates for laboratory microvascular repair. In this study, a total of 300 standard microsurgical anastomoses were performed on rat femoral veins. The patency of each anastomosis was assessed at regular intervals within a 2-week study period. These results showed that the majority of venous occlusions occurred within 1 day after repair. Recanalization of the occluded vein was first seen at day 3 postoperatively. Recanalization was observed over a 2-week postoperative period with increasing frequency. The authors conclude that the optimal time to assess the technical outcome of experimental venous patency is 1 to 2 days after the repair.

KEYWORD

Microsurgery - anastomosis - vein - thrombosis - recanalization

REFERENCES

  • 1 Eddy C A, Laufe L E, Dunn R L, Gibson J W. The use of prostacyclin analogue containing suture for the prevention of postoperative venous thrombosis in the rat.  Plast Reconstr Surg . 1986;  78 504-512
    PubMedSearch in Google Scholar
  • 2 Bas L, May J W, Handren J, Fallon J. End-to-end versus end-to-side microvascular anastomosis patency in experimental venous repairs.  Plast Reconstr Surg . 1986;  77 442-450
    CrossrefPubMedSearch in Google Scholar
  • 3 Hayhurst J W, O'Brien Mc C B. An experimental study of microvascular technique, patency rates and related factors.  Br J Plast Surg . 1975;  28 128-132
    CrossrefPubMedSearch in Google Scholar
  • 4 Carter P D. Suture and non-suture methods of small vein anastomosis.  Arch Surg . 1962;  84 350-352
    PubMedSearch in Google Scholar
  • 5 Blumoff R L, Proctor H J, Johnson G. Recanalization of a saphenous vein interposition venous graft.  J Trauma . 1981;  21 407-408
    PubMedSearch in Google Scholar
  • 6 Flanc C. An experimental study of the recanalization of arterial and venous thrombi.  Br J Surg . 1968;  55 519-524
    PubMedSearch in Google Scholar
  • 7 Wu A V, Mansfield A. The fibrinolytic activity of the vein following venous stasis.  Br J Surg . 1979;  66 637-639
    PubMedSearch in Google Scholar
  • 8 Peduzzi M, De Rosa V, Fonda S, Coccheri S. Haemostatic studies in retinal vein occlusion: fibrinolytic response to venostasis as a prognostic factor for spontaneous recanalization.  Thrombosis Res . 1981;  24 105-118
    CrossrefPubMedSearch in Google Scholar
  • 9 Kersh R A, Handren J, Hergrueter C, May J W. Microvascular surgical experimental thrombosis model: rationale and design.  Plast Reconstr Surg . 1989;  83 866-872
    PubMedSearch in Google Scholar
  • 10 Petry J J, Burstein S, Chang W H. Prostacyclin production by vein grafts in the arterial circulation: a study in rats.  Prostaglandins Leukotrienes Med . 1982;  9 511-516
    CrossrefPubMedSearch in Google Scholar
  • 11 Porter J M, Goodnight S H. The role of the platelet in coagulation and clinical thrombotic events.  Am J Surg . 1977;  134 231-235
    CrossrefPubMedSearch in Google Scholar
  • 12 Zinberg E M, Choo D I, Zotter L A. Effect of heparinized irrigating solutions on patency of experimental microvascular anastomoses.  Microsurgery . 1989;  10 103-107
    CrossrefPubMedSearch in Google Scholar
  • 13 Cooley B, Gould J. Rat femoral vein-to-vein grafts as a microvascular practice model: factors that influence patency.  Microsurgery . 1991;  12 43-45
    PubMedSearch in Google Scholar
  • 14 Jacobs G R, Reinisch J F, Puckett C L. Quantitative analysis of plasminogen activator in small arteries by modified fibrin plates.  Microsurgery . 1982;  3 147-150
    PubMedSearch in Google Scholar
  • 15 Johnson P C, Barker J H. Thrombosis and antithrombotic therapy in microvascular surgery.  Clin Plast Surg . 1992;  19 799-807
    PubMedSearch in Google Scholar
  • 16 Arnljots B, Dougan P, Wieslander J B. Platelet accumulation and thrombus formation after microarterial injury: an experimental study in rabbits.  Scand J Plast Reconstr Surg Hand Surg . 1994;  28 167-175
    PubMedSearch in Google Scholar
  • 17 Salemark L, Wieslander J B, Dougan P, Arnljots B. Studies of the antithrombotic effects of dextran 40 following microarterial trauma.  Br J Plast Surg . 1991;  44 15-22
    CrossrefPubMedSearch in Google Scholar
  • 18 Strecker W B, Wood M B, Schroeder A R. Stasis-induced thrombosis of rat microvascular anastomosis.  J Reconstr Microsurg . 1987;  4 69-73
    Thieme ConnectPubMedSearch in Google Scholar
  • 19 Morecraft R, Blair W F, Chang L. Histopathology of microvenous repair.  Microsurgery . 1985;  6 219-228
    PubMedSearch in Google Scholar
  • 20 Lan M, Li X L, Cooley B C, Gould J S. Microvascular salvage procedures with adjuvant antithrombotic therapy for restitution of patency in a rat model.  J Reconstr Microsurg . 1992;  8 201-205
    PubMedSearch in Google Scholar
  • 21 Smahel J. Spontaneous anastomosis of transected vessels.  Ann Plast Surg . 1991;  26 365-369
    PubMedSearch in Google Scholar