Am J Perinatol 2002; 19(1): 009-016
DOI: 10.1055/s-2002-20176
ORIGINAL ARTICLE

Copyright © 2002 by Thieme Medical Publishers, Inc., 333 Seventh Avenue, New York, NY 10001, USA. Tel.: +1(212) 584-4662

Contemporary Trends in the Management of Delivery at 23 Weeks' Gestation

Thomas F. McElrath1 , Errol R.  Norwitz1 , Nawal Nour1 , Julian N. Robinson2
  • 1Department of Obstetrics, Gynecology, and Reproductive Biology, Brigham & Women's Hospital, Harvard Medical School, Boston, Massachusetts
  • 2Department of Obstetrics and Gynecology, Columbia-Presbyterian Medical Center, Columbia University, New York, New York
Weitere Informationen

Publikationsverlauf

Publikationsdatum:
18. Februar 2002 (online)

ABSTRACT

The objective of this study is to investigate the current understanding of neonatal survival and the willingness to provide aggressive obstetric intervention at the limit of fetal viability among practicing perinatologists in the United States. A pretested survey was mailed to members of the Society for Maternal Fetal Medicine. The survey identified the practitioner's opinion of the lowest limit of viability and gestational ages at which antenatal steroids and cesarean section would first be provided. We also attempted to identify practitioner knowledge of survival at 23 and 24 weeks' gestation and years of perinatal practice. Of the 1244 surveys mailed to members of the Society for Maternal-Fetal Medicine practicing in the United States, 462 practitioners replied for a 37% response rate. Fifty percent considered the lower limit of viability to be 24 weeks' and 44.3% believed the lower limit of viability to be 23 weeks' gestation. Among respondents, the majority estimated a 0 to 10% survival rate at 23 weeks' and 25 to 50% survival rate at 24 weeks. Only 13% of respondents correctly estimates survival at 23 weeks' gestation as >25%, and only 17% correctly estimated survival at 24 weeks' at >50%. Among practitioners, 43.6% would first give antenatal steroids after 24 weeks' gestation but 55.6%would administer steroids before the beginning of week 24. Twenty-eight percent would routinely monitor a fetus less than 24 weeks' gestation. Consistent with this observation, 21% would perform a cesarean section before 24 weeks' gestation. We find that respondents underestimate the consensus in the most recent literature on survival of infants born at 23 to 24 weeks. This underestimation may lead to a limitation in interventions offered.

REFERENCES

  • 1 Paul R H, Koh K S, Monfared A H. Obstetric factors influencing outcome in infants weighing 1001 to 1500 grams.  Am J Obstet Gynecol . 1979;  133 503-508
  • 2 Bottoms S F, Paul R H, Iams J D. Obstetric determinants of neonatal survival: influence of willingness to perform cesarean delivery on survival of extremely low-birth-weight infants.  Am J Obstet Gynecol . 1997;  176 960-966
  • 3 Hack M, Fanaroff A A. Outcomes of extremely-low-birth-weight infants between 1982 and 1988.  N Engl J Med . 1989;  321 1642-1647
  • 4 Hack M. Outcomes of children of extremely low birthweight and gestational age in the 1990's.  Early Human Dev . 1999;  53 193-218
  • 5 Allen M C, Donohue P K, Dusman A E. The limit if viability: neonatal outcome of infants born at 22 to 25 weeks' gestation.  N Engl J Med . 1993;  329 1597-1601
  • 6 Perinatal care at the threshold of viability. American Academy of Pediatrics Committee on Fetus and Newborn. American College of Obstetricians and Gynecologists Committee on Obstetric Practice.  Pediatrics . 1995;  96 974-976
  • 7 Draper E S, Manktelow B, Field D J, James D. Prediction of survival for preterm births by weight and gestational age: retrospective population based study.  BMJ . 1999;  319 1093-1097
  • 8 Emsley H CA, Wardle S P, Sims D G, Chiswick M L, D'Souza S W. Increased survival and deteriorating developmental outcomes in 23 to 25 week old gestation infants, 1990-4 compared with 1984-9.  Arch Dis Child . 1998;  78 99-104
  • 9 Hussain N, Galal M, Ehrenkranz R A, Herson V C, Rowe J C. Pre-discharge outcomes of 22-27 weeks' gestational age infants born at tertiary care centers in Connecticut implications for perinatal management.  Conn Med . 1998;  62 131-137
  • 10 O'Shea T M, Kleinpeter K L, Goldstein D J, Jackson B W, Dillard R G. Survival and developmental disability in infants with birth weights of 501 to 800 gram, born between 1979 and 1994.  Pediatrics . 1997;  100 982-986
  • 11 Kramer W B, Saade G R, Goodrum L, Belfort M, Moise Jr J K. Neonatal outcome after active perinatal management of the very premature infant between 23 and 27 weeks' gestation.  J Perinatol . 1997;  17 439-443
  • 12 Holtrop P C, Ertzbischoff L M, Roberts C L, Batton D G, Lorenz R P. Survival and short-term outcome in newborns of 23 to 25 weeks' gestation.  Am J Obstet Gynecol . 1994;  170 1266-1270
  • 13 Stevenson D K, Wright L I, Lemons J A. Very low birth weight outcomes of the National Institute of Child Health and Human Development Neonatal Research Network, January 1993 through December 1994.  Am J Obstet Gynecol . 1998;  179 1632-1639
  • 14 Wood N S, Marlow N, Costeloe K, Gibson A T, Wilkinson A R. Neurologic and developmental disability after extremely preterm birth.  N Engl J Med . 2000;  343 378-384
  • 15 McElrath T F, Robinson J N, Ecker J L, Ringer S A, Norwitz E R. Neonatal outcome of infants born at 23 weeks' gestation.  Obstet Gynecol . 2001;  97 49-52
  • 16 Paul R H, Koh K S, Monfared A H. Obstetric factors influencing outcome in infants weighing from 1,001 to 1,500 grams.  Am J Obstet Gynecol . 1979;  133 503-507
  • 17 Goldenberg R L, Nelson K G, Dyer R L, Wayne J. The variability of variability: the effect of physicians' perceptions of viability on the survival of very low-birth weight infants.  Am J Obstet Gynecol . 1982;  143 678-684
  • 18 Morse S B, Haywood J L, Goldenberg R L, Bronstein J, Nelson K G, Carlo W A. Estimation of neonatal outcome and perinatal therapy use.  Pediatrics . 2000;  105 1046-1050
  • 19 Society for Maternal Fetal-Medicine. 2001 Membership Statistics. Washington, DC: Society for Maternal-Fetal Medicine 2001
  • 20 Amon E, Shyken J M, Sibai B M. How small is too small and how early is too early?.  <~>A survey of American obstetricians specializing in high-risk pregnancies. Am J Perinatol . 1992;  9 17-21
  • 21 O'Brien J M, Barton J R, Donaldson E S. The management of placenta percreta: conservative and operative strategies.  Am J Obstet Gynecol . 1996;  175 1623-1628
  • 22 Wilson A L, Wellman L R, Fenton L J, Witzke D B. What physicians know about the prognosis of preterm newborns.  Am J Dis Child . 1983;  137 551-554
  • 23 Sanders M R, Donohue P K, Oberdorf M A, Rosenkrantz T S, Allen M C. Perceptions of the limit of viability: neonatologists' attitudes toward extremely premature infants.  J Perinatol . 1995;  15 494-502
  • 24 Weiss E, Martinez M, Greeman H, Partridge J C. Obstetric management of ELBW infants: perceptions of infant viability and parental counseling practice.  Pediatr Rev . 1997;  30 A162