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DOI: 10.1055/s-2002-20251
© Georg Thieme Verlag Stuttgart · New York
Ellagitannins from Lagerstroemia speciosa as Activators of Glucose Transport in Fat Cells
Publikationsverlauf
March 29, 2001
June 10, 2001
Publikationsdatum:
22. Februar 2002 (online)
![](https://www.thieme-connect.de/media/plantamedica/200202/lookinside/thumbnails/10.1055-s-2002-20251-1.jpg)
Abstract
Glucose transport enhancers were searched for in Lagerstroemia speciosa, a Philippine local herbal medicine used for diabetes mellitus. Bioassay-guided fractionation of the aqueous acetone extract of the leaves afforded three active ellagitannins, lagerstroemin, flosin B and reginin A, identified by NMR and optical rotation. These compounds increased glucose uptake of rat adipocytes, and could be responsible for lowering the blood glucose level.
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Prof. Kazuo Yamasaki
Institute of Pharmaceutical Sciences
Faculty of Medicine
Hiroshima University
1-2-3 Kasumi
Minami-ku
Hiroshima 734-8551
Japan
eMail: yamasaki@pharm.hiroshima-u.ac.jp
Fax: +81-82-257-5289