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DOI: 10.1055/s-2002-20254
© Georg Thieme Verlag Stuttgart · New York
New Lupane Glycosides from Pulsatilla chinensis
Publication History
February 10, 2001
June 17, 2001
Publication Date:
22 February 2002 (online)
![](https://www.thieme-connect.de/media/plantamedica/200202/lookinside/thumbnails/10.1055-s-2002-20254-1.jpg)
Abstract
Two new lupane glycosides along with five known triterpenoids were isolated from the roots of Pulsatilla chinensis (Ranunculaceae). The structures of the new glycosides were determined to be 3-O-β-D-glucopyranosyl(1→3)-α-L-arabinopyranosyl-23-hydroxybetulinic acid 28-O-α-L-rhamnopyranosyl(1→4)-β-D-glucopyranosyl(1→6)-β-D-glucopyranosyl ester (pulsatilloside D, 6) and 3-O-[β-D-glucopyranosyl(1→4)][α-L-rhamnopyranosyl(1→2)]-α-L-arabinopyranosyl-23-hydroxybetulinic acid 28-O-α-L-rhamnopyranosyl(1→4)-β-D-glucopyranosyl(1→6)-β-D-glucopyranosyl ester (pulsatilloside E, 7) by spectroscopic analysis and chemical methods. The compounds were evaluated for cytotoxic activities against K-562 human leukemia and HeLa cells.
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Prof. Chun-Tao Che
School of Chinese Medicine
The Chinese University of Hong Kong
Shatin
Hong Kong
Email: chect@cuhk.edu.hk
Fax: +852-2603-7203
Phone: +852-2609-8130