Endoscopy 2002; 34(3): 199-202
DOI: 10.1055/s-2002-20291
Original Article

© Georg Thieme Verlag Stuttgart · New York

Comparative Study of Portal Hypertensive Gastropathy in Schistosomiasis and Hepatic Cirrhosis

D.  Marques Chaves 1 , P.  Sakai 1 , M.  Mucenic 1 , K.  Iriya 2 , Y.  Iriya 2 , S.  Ishioka 1
  • 1Endoscopy Service, University of São Paulo School of Medicine, São Paulo, Brazil
  • 2Department of Pathology, University of São Paulo School of Medicine, São Paulo, Brazil
Weitere Informationen

Publikationsverlauf

23 May 23 2001

15 October 2001

Publikationsdatum:
22. Februar 2002 (online)

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Background and Study Aims: Portal hypertensive gastropathy (PHG) is a common finding in chronic liver disease, but it has not been evaluated in hepatosplenic schistosomiasis, a significant cause of noncirrhotic portal hypertension worldwide. Our study was aimed at comparing cirrhosis with hepatosplenic schistosomiasis with regard to the endoscopic and histological findings of PHG.
Patients and Methods: We included 43 patients with a history of upper digestive hemorrhage, 22 with cirrhosis and 21 with schistosomiasis, without previous surgical or endoscopic treatment. Upper digestive endoscopies with macrobiopsies of the gastric body were prospectively performed in all cases.

Results: The endoscopic signs of PHG were more prevalent in cirrhosis than schistosomiasis (81.8 % vs. 33.3 %; P < 0.05), and the mosaic pattern was the main finding. Histological abnormalities were evenly distributed.

Conclusions: In agreement with other investigations, this study shows a lower prevalence of endoscopic findings of portal hypertensive gastropathy in noncirrhotic diseases. This difference cannot be explained by the underlying microscopic alterations, which were similar in both groups, suggesting that other factors must play a role in its pathogenesis.