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Horm Metab Res 2002; 34(2): 107-108
DOI: 10.1055/s-2002-20526
DOI: 10.1055/s-2002-20526
Letter to the Editor
© Georg Thieme Verlag Stuttgart · New York
Does Gliclazide Stimulate First-Phase, Second-Phase, or Both Phases of Insulin Release?
Weitere Informationen
Publikationsverlauf
29 October 2001
31 October 2001
Publikationsdatum:
04. März 2002 (online)

References
- 1 Ligtenberg J JM, Reitsma W D, van Haeften T W. Gliclazide mainly affects insulin secretion in second phase of type 2 diabetes mellitus. Horm Metab Res. 2001; 33 361-364
- 2 Delia Casa L, Del Rio G, Glaser B, Cerasi E. Effect of 6-month gliclazide treatment on insulin release and sensitivity to endogenous insulin in NIDDM: Role of initial continuous subcutaneous insulin infusion-induced normoglycemia. Amer J Med. 1990; 90 37S-45S
- 3 Cerasi E, Luft R, Efendic S. Decreased sensitivity of the pancreatic beta-cells to glucose in prediabetic and diabetic subjects. A glucose dose-response study. Diabetes. 1972; 21 224-234
- 4 Nesher R, Della Casa L, Litvin Y, Sinai J, Del Rio G, Pevsner B, Wax Y, Cerasi E. Insulin deficiency and insulin resistance in Type 2 (non-insulin-dependent) diabetes. Quantitative contributions of pancreatic and peripheral responses to glucose homeostasis. Eur J Clin Invest. 1987; 17 266-274
- 5 Steiner K E, Bowles C R, Mouton S M, Williams P E, Cherrington A D. The relative importance of first and second phase insulin secretion in countering the action of glucagon on glucose turnover in the conscious dog. Diabetes. 1982; 31 964-972
- 6 Getty L, Hamilton-Wessler M, Ader M, Dea M K, Bergman R N. Biphasic insulin secretion during intravenous glucose tolerance test promotes optimal interstitial insulin profile. Diabetes. 1998; 47 1941-1947
Prof. Dr. Erol Cerasi, M.D., Ph.D.
Hadassah University Hospital
PO Box 12000 · 91120 Jerusalem · Israel
Telefon: + 972 (2) 642 07 40
Fax: + 972 (2) 642 07 40
eMail: Erol.Cerasi@huji.ac.il