Planta Medica, Inhaltsverzeichnis Planta Med 2002; 68(3): 253-257DOI: 10.1055/s-2002-23136 Original Paper Natural Product Chemistry © Georg Thieme Verlag Stuttgart · New York Taxuyunnanines S-V, New Taxoids from Taxus yunnanensis Sheng-Hong Li1 , Hong-Jie Zhang2 , Xue-Mei Niu1 , Ping Yao2 , Han-Dong Sun1 , Harry H. S. Fong2 1Laboratory of Phytochemistry, Kunming Institute of Botany, Academia Sinica, Kunming, Yunnan, China 2Program for Collaborative Research in the Pharmaceutical Sciences, College of Pharmacy, University of Illinois at Chicago, Chicago, Illinois, U.S.A. Artikel empfehlen Abstract Artikel einzeln kaufen Abstract Four new 11(15→1)-abeotaxoids with an opened oxetane ring system, taxuyunnanines S, T, U and V (1 - 4) were isolated from the bark of Taxus yunnanensis. Taxuyunnanine S (1), is the most hydroxylated abeotaxoid discovered to date from Taxus species. The structures were determined by spectroscopic means including 1D and 2D NMR experiments. Key words Taxus yunnanensis - Taxaceae - bark - 11(15→1)-abeotaxoids - taxuyunnanines S, T, U and V - 1D and 2D NMR Volltext Referenzen References 1 Rao C, Liu X, Zhang P L, Chen W M, Fang Q C. Application of high-speed countercurrent chromatography for the isolation of natural products and preparative isolation of taxane diterpenoids and diterpene alkaloids. Yaoxue Xuebao. 1991; 26 510-4 2 Xiang W, Zhang H J, Run D C, Sun H D. Contents of taxol and four other taxane diterpenoids in Taxus yunnanensis . Zhiwu Ziyuan Yu Huanjing. 1997; 6 56-7 3 Zhang H J, Takeda Y, Minami Y, Yoshida K, Unemi N, Mu Q, Xiang W, Sun H D. Taxanes from the roots of Taxus yunnanensis . Yunnan Zhiwu Yanjiu. 1993; 15 424-6 4 Zhang H J, Sun H D, Takeda Y. Four new taxanes from the roots of Taxus yunnanensis . J. Nat.Prod.. 1995; 58 1153-9 5 Zhang H J, Mu Q, Xiang W, Yao P, Sun H D, Takeda Y. Intramolecular transesterified taxanes from Taxus yunnanensis. . Phytochemistry. 1997; 44 911-5 6 Zhang H J, Takeda Y, Sun H D. Taxanes from Taxus yunnanensis . Phytochemistry. 1995; 39 1147-51 7 Li S H, Zhang H J, Yao P, Sun H D. Two new taxoids from Taxus yunnanensis . Chinese Chemistry Letters. 1998; 9 017-20 8 Li S H, Zhang H J, Yao P, Sun H D, Fong H HS. Rearranged taxanes from the bark of Taxus yunnanensis . Journal of Natural Products. 2000; 63 1488-91 9 Li S H, Zhang H J, Yao P, Sun H D, Fong H HS. New taxane diterpenoids from the bark of Taxus yunnanensis . Phytochemistry 2001: in press 10 Zhang S, Lee C TL, Kashiwada Y, Chen K J. Yunantaxusin A, a new 11(15->1)-abeo-taxane from Taxus yunnanensis . Journal of Natural Products. 1994; 57 1580-3 Dr. Dr. Hongjie Zhang and Harry H. S. Fong Program for Collaborative Research in the Pharmaceutical Sciences, M/C 877 College of Pharmacy University of Illinois at Chicago 833 S. Wood St. Chicago IL 60612 U.S.A. eMail: zhanghj@uic.edu and hfong@uic.edu Fax: +1-312-413-5894
