Subscribe to RSS
DOI: 10.1055/s-2002-23136
© Georg Thieme Verlag Stuttgart · New York
Taxuyunnanines S-V, New Taxoids from Taxus yunnanensis
Publication History
April 30, 2001
August 5, 2001
Publication Date:
25 March 2002 (online)

Abstract
Four new 11(15→1)-abeotaxoids with an opened oxetane ring system, taxuyunnanines S, T, U and V (1 - 4) were isolated from the bark of Taxus yunnanensis. Taxuyunnanine S (1), is the most hydroxylated abeotaxoid discovered to date from Taxus species. The structures were determined by spectroscopic means including 1D and 2D NMR experiments.
Key words
Taxus yunnanensis - Taxaceae - bark - 11(15→1)-abeotaxoids - taxuyunnanines S, T, U and V - 1D and 2D NMR
References
- 1 Rao C, Liu X, Zhang P L, Chen W M, Fang Q C. Application of high-speed countercurrent chromatography for the isolation of natural products and preparative isolation of taxane diterpenoids and diterpene alkaloids. Yaoxue Xuebao. 1991; 26 510-4
- 2 Xiang W, Zhang H J, Run D C, Sun H D. Contents of taxol and four other taxane diterpenoids in Taxus yunnanensis . Zhiwu Ziyuan Yu Huanjing. 1997; 6 56-7
- 3 Zhang H J, Takeda Y, Minami Y, Yoshida K, Unemi N, Mu Q, Xiang W, Sun H D. Taxanes from the roots of Taxus yunnanensis . Yunnan Zhiwu Yanjiu. 1993; 15 424-6
- 4 Zhang H J, Sun H D, Takeda Y. Four new taxanes from the roots of Taxus yunnanensis . J. Nat.Prod.. 1995; 58 1153-9
- 5 Zhang H J, Mu Q, Xiang W, Yao P, Sun H D, Takeda Y. Intramolecular transesterified taxanes from Taxus yunnanensis. . Phytochemistry. 1997; 44 911-5
- 6 Zhang H J, Takeda Y, Sun H D. Taxanes from Taxus yunnanensis . Phytochemistry. 1995; 39 1147-51
- 7 Li S H, Zhang H J, Yao P, Sun H D. Two new taxoids from Taxus yunnanensis . Chinese Chemistry Letters. 1998; 9 017-20
- 8 Li S H, Zhang H J, Yao P, Sun H D, Fong H HS. Rearranged taxanes from the bark of Taxus yunnanensis . Journal of Natural Products. 2000; 63 1488-91
- 9 Li S H, Zhang H J, Yao P, Sun H D, Fong H HS. New taxane diterpenoids from the bark of Taxus yunnanensis . Phytochemistry 2001: in press
- 10 Zhang S, Lee C TL, Kashiwada Y, Chen K J. Yunantaxusin A, a new 11(15->1)-abeo-taxane from Taxus yunnanensis . Journal of Natural Products. 1994; 57 1580-3
Dr. Dr. Hongjie Zhang and Harry H. S. Fong
Program for Collaborative Research in the Pharmaceutical Sciences, M/C 877
College of Pharmacy
University of Illinois at Chicago
833 S. Wood St.
Chicago
IL 60612
U.S.A.
Email: zhanghj@uic.edu and hfong@uic.edu
Fax: +1-312-413-5894