Abstract
Two spasmolytic diterpene acids, ent-beyer-15-en-19-oic acid and ent-kaur-16-en-19-oic acid, have been isolated from the roots of Viguiera hypargyrea by bioassay-guided fractionation. Beyerenoic acid was also active against Staphylococcus aureus, Enterococcus feacalis and Candida albicans.
References
-
1
Blake S F.
A revision of genus Viguiera
.
Contribution Gray Herbarium Harvard University.
1918;
54
11-6
-
2 Martínez M. Catálogo de Plantas medicinales de México. Ed. Botas 1969: 45
-
3
Alvarez L, Mata R, Delgado G, Romo de Vivar A.
Sesquiterpene lactones from Viguiera hypargyrea
.
Phytochemistry.
1985;
24
2973-6
-
4
Villarreal M L, Alvarez L, Alonso D, Navarro V, García P, Delgado G.
Cytotoxic and antimicrobial screening of selected terpenoids from Mexican Asteraceae species.
Journal of Ethnopharmacology.
1994;
42
25-9
-
5
Marquina S, Maldonado N, Garduño-Ramírez M L, Aranda E, Villarreal M L, Navarro N, Bye R, Delgado G, Alvarez L.
Bioactive oleanolic acid saponins and other constituents from the roots of Viguiera decurrens
.
Phytochemistry.
2001;
56
93-7
-
6
Coll C, Bowden E.
The application of vacuum liquid chromatography to the separation of terpene mixtures.
Journal of Natural Products.
1986;
49
934-6
-
7
Enriquez R G, Escobar L I, Romero M L, Chavez M A, Lozoya X.
Determination of grandiflorenic acid in organic and aqueous extracts of Montanoa tomentosa (zoapatle) by reversed-phase high-performance liquid chromatography.
Journal of Chromatography.
1983;
258
297-301
-
8
Delgado G, Romo de Vivar A, Cardenas J, Pereda-Miranda R, Huerta E.
Ent-beyerene and ent-atisane diterpenes from Viguiera insignis
.
Phytochemistry.
1984;
23
2285-8
-
9
Reynolds W T, Enriquez R G, Escobar L I, Lozoya X.
Total assignment of 1H and 13C spectra of kauradien-9(11),16-oic acid with the aid of heteronuclear correlated 2D spectra optimized for geminal and vicinal 13C-1H coupling constants: or what to do when ”INADEQUATE” is impossible.
Canadian Journal of Chemistry.
1984;
62
2421-5
-
10 Lennette E M, Balows A, Hansler W J, Shadomy H J. (Eds) Manual of Clinical Microbiology pp. 1985: 143-53
-
11
Lozoya X, Becerril G, Martínez M.
Intraluminal perfusion model of in vitro guinea pig’s ileum as a model of study of the antidiarrheic properties of the guava (Psidium guajava).
Archivos de Investigacion Medica (México).
1990;
21
155-62
-
12
Tortoriello J and Aguilar-Santamaría L.
Evaluation of the calcium-antagonist, antidiarrhoeic and central nervous system activities of Baccharis serraefolia
.
Journal of Ethnopharmacol..
1996;
53
157-63
Dra. Laura Alvarez
Centro de Investigaciones Químicas
Universidad Autónoma del Estado de Morelos
Av. Universidad 1001, Col. Chamilpa, Cuernavaca 62210 Morelos
Mexico
Email: lalvarez@intermor.net.mx
Fax: +52-73-297997