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Planta Med 2002; 68(4): 375-376
DOI: 10.1055/s-2002-26757
DOI: 10.1055/s-2002-26757
Letter
© Georg Thieme Verlag Stuttgart · New York
Shogaols from Zingiber officinale Protect IMR32 Human Neuroblastoma and Normal Human Umbilical Vein Endothelial Cells from β-Amyloid(25 - 35) Insult
Further Information
Publication History
April 11, 2001
October 21, 2001
Publication Date:
02 May 2002 (online)
![](https://www.thieme-connect.de/media/plantamedica/200204/lookinside/thumbnails/10.1055-s-2002-26757-1.jpg)
Abstract
From the rhizome of Zingiber officinale L. (Zingiberaceae), four shogaols that protect IMR32 human neuroblastoma and normal human umbilical vein endothelial cells from β-amyloid(25 - 35) insult at EC50 = 4.5 - 81 μM were isolated. The efficacy of cell protection from β-amyloid(25 - 35) insult by these shogaols was shown to improve as the length of the side chain increases.
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