Synthesis of New Fluorine Containing Triazolo- and Tetrazolopyrimidines

Abstract

The reaction of 1,1,1-trifluoro-4-(sulfonyl)-but-3-ene-2,2-dioles 1a,b with corresponding aminoazoles was investigated. A new simple and efficient way for the regioselective synthesis of 5-CF₃ or 7-CF₃ triazolo- and tetrazolopyrimidines is described.

Key words

cycloaddition - heterocycles - triazolopyrimidine - tetrazolopyrimidine - sulfones

References

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Krasovsky, A. L.; Nenajdenko, V. G.; Balenkova, E. S. Synthesis 2002, in press.

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Krasovsky, A. L.; Moiseev A. M.; Nenajdenko, V. G.; Balenkova, E. S. Khim. Het. Soedin 2002, in press.