Reaction of (Alkylthio)chloroacetylenes with Thiosemicarbazones: A Route to Functionalized Thiazoles

Svetlana G. D’yachkova; Elena A. Nikitina; Ludmila I. Larina; Peter E. Ushakov; Nina K. Gusarova; Lidiya M. Sinegovskaya; Boris A. Trofimov

doi:10.1055/s-2002-28518

PAPER

Reaction of (Alkylthio)chloroacetylenes with Thiosemicarbazones: A Route to Functionalized Thiazoles

Svetlana G. D’yachkova*, Elena A. Nikitina, Ludmila I. Larina, Peter E. Ushakov, Nina K. Gusarova, Lidiya M. Sinegovskaya, Boris A. Trofimov
A. E. Favorsky Institute of Chemistry, Siberian Branch of the Russian Academy of Sciences, 664033 Irkutsk, Russia
Fax: +7(395)2396046; e-Mail: dsg@irioch.irk.ru;

Abstract

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Abstract

(Alkylthio)chloroacetylenes 1 react with thiosemicarbazones 2 at room temperature in a medium of aliphatic ketone to form hydrochlorides of 2-alkanone-N-[4-(organylthio)-1,3-thiazol-2-yl]hydrazones 3 in yields of up to 65%.

Key words

(alkylthio)chloroacetylenes - thiosemicarbazones - hydrochlorides of 2-alkanone-N-[4-(organylthio)-1,3-thiazol-2-yl]hydrazones - 2-alkanon-N-[4-(organylthio)-1,3-thiazol-2-yl]hydra-zones - synthesis

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Referenzen

References

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