Palladium- or Nickel-Catalyzed Cross-Coupling of Organotitanium Reagents with Aryl Triflates and Halides

Jin Wook Han; Norihito Tokunaga; Tamio Hayashi

doi:10.1055/s-2002-31930

LETTER

Palladium- or Nickel-Catalyzed Cross-Coupling of Organotitanium Reagents with Aryl Triflates and Halides

Jin Wook Han, Norihito Tokunaga, Tamio Hayashi*
Department of Chemistry, Graduate School of Science, Kyoto University, Sakyo, Kyoto 606-8502, Japan
Fax: +81(75)7533988; e-Mail: thayashi@kuchem.kyoto-u.ac.jp;

Abstract

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Abstract

The reaction of organotitanium reagents, methyltitanium triisopropoxide [MeTi(i-PrO)₃] and phenyltitanium triisopropoxide [PhTi(i-PrO)₃], with aryl triflates and halides proceeded in the presence of 1.0 mol% of palladium catalyst coordinated with (R*)-N,N-dimethyl-1-[(S*)-2-(diphenylphosphino)ferrocenyl]ethylamine [(R*)-(S*)-PPFA] in refluxing THF to give a quantitative yield of the corresponding cross-coupling products.

Key words

cross-coupling - organotitanium - palladium catalyst - aryl triflate - aryl halide

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References

References and Notes

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