Clin Colon Rectal Surg 2002; 15(2): 145-156
DOI: 10.1055/s-2002-32063
Copyright © 2002 by Thieme Medical Publishers, Inc., 333 Seventh Avenue, New York, NY 10001, USA. Tel.: +1(212) 584-4662

Rectal Villous Adenomas

Charles B. Whitlow
  • Central Texas Colorectal and General Surgery Center, Waco, TX
Weitere Informationen

Publikationsverlauf

Publikationsdatum:
06. Juni 2002 (online)

ABSTRACT

Villous tumors of the rectum account for 40 to 90% of all large bowel villous adenomas. Although increasing size is associated with risk of malignancy, villous tumors can become very large or encompass the entire rectum without containing malignancy. Bleeding, diarrhea, mucous discharge, prolapse, and constipation are common presenting symptoms. Clinical exam, endorectal ultrasound, and biopsy identify nearly all invasive malignancies in these tumors. Appropriate treatment is removal of the tumor while preserving anal sphincter function. The method of treatment is determined by the tumor location, tumor size, and patient factors (comorbidities, treatment preference, and existing sphincter function). Simple snare excision treats pedunculated villous adenomas. Low- and midrectal tumors are treated by transanal techniques, including snare excision with staged fulguration, transanal excision, or circumferential mucosectomy. These approaches offer low morbidity and preserve sphincter function but carry a substantial rate of recurrence, and therefore close postoperative follow-up is an integral part of this type of management. Recurrences are usually asymptomatic and can be treated with fulguration or transanal excision. Transabdominal or laparoscopic rectal excision best treats larger tumors and more proximal rectal villous tumors. Abdominoperineal resection should rarely be necessary to treat benign rectal villous tumors.

REFERENCES

  • 1 Bacon H E, Lowell E J, Trimpi H D. Villous papillomas of the colon and rectum: a study of twenty-eight cases with end results of treatment over a five-year period.  Surgery . 1954;  35 77-87
  • 2 Samson R B, Andarsio C O. Intrarectal resection of villous adenoma.  Dis Colon Rectum . 1962;  8 446-450
  • 3 Quan S HQ, Castro E B. Papillary adenomas (villous tumors): a review of 215 cases.  Dis Colon Rectum . 1971;  14 267-280
  • 4 Hanley P H, Hines M O, Ray J E. Villous tumors: experience with 217 patients.  Am Surg . 1971;  37 190-197
  • 5 Welch J P, Welch C E. Villous adenomas of the colorectum.  Am J Surg . 1976;  131 185-191
  • 6 Thomson J PS. Treatment of sessile villous and tubulovillous adenomas of the rectum: experience of St.  Mark's Hospital 1963-1972. Dis Colon Rectum . 1977;  20 467-472
  • 7 Galandiuk S, Fasio V, Jagelman D G. Villous and tubulovillous adenomas of the colon and rectum: a retrospective review, 1954-1985.  Am J Surg . 1987;  153 41-47
  • 8 Hanley P H. Treatment of large villous tumors of the lower rectum by multiple-stage fulguration.  Tex Med . 1976;  72 98-101
  • 9 McKittrick L S, Wheelock Jr C F. Carcinoma of the Colon.  Springfield, IL: Charles C Thomas 1954: 61-63
  • 10 Schrock L C, Polk H C. Rectal villous adenomas producing hypokalemia.  Am Surg . 1974;  40 54-59
  • 11 Fenoglio-Preiser C, Pascal R R, Perzin K H. Adenomas: tumors of the intestines.  Washington, DC: Armed Forces Institute of Pathology 1990: 105-108
  • 12 Balazs M. Electron-microscopic study of the villous adenoma of the colon.  Virch Arch Anat Pathol Histol . 1980;  387 193-205
  • 13 Sunderland D A, Binkley G E. Papillary adenomas of the large intestine. A clinical and morphologic study of forty-eight cases.  Cancer . 1948;  1 184-207
  • 14 Wheat M W, Ackerman L V. Villous adenomas of the large intestine. Clinicopathologic evaluation of 50 cases of villous adenomas with emphasis on treatment.  Ann Surg . 1958;  147 476-487
  • 15 Bacon H E, Eisenberg S W. Papillary adenoma or villous tumor of the rectum and colon.  Ann Surg . 1971;  174 1002-1008
  • 16 Jahadi M R, Baldwin A. Villous adenomas of the colon and rectum.  Am J Surg . 1975;  130 729-732
  • 17 Shinya H, Wolff W I. Morphology, anatomic distribution and cancer potential of colonic polyps. An analysis of 7,000 polyps endoscopically removed. Ann Surg .  1979;  190 679-683
  • 18 Scoma J A. Management of benign villous adenomas of the entire rectum.  Dis Colon Rectum . 1978;  21 630-632
  • 19 Groff W, Rubin R J, Salvati E P, Eisenstat T P. A method of management of a circumferential villous tumor of the rectum.  Dis Colon Rectum . 1981;  24 151-154
  • 20 Keck J O, Schoetz D J, Roberts P L. Rectal mucosectomy in the treatment of giant rectal villous tumors.  Dis Colon Rectum . 1995;  38 233-238
  • 21 Nivatvongs S, Nicholson J D, Rothenberger D A. Villous adenomas of the rectum: the accuracy of clinical assessment.  Surgery . 1980;  87 549-551
  • 22 Glaser F, Schlag P, Herfarth C. Endorectal ultrsonography for the assessment of invasion of rectal tumors and lymph node involvement.  Br J Surg . 1990;  77 883-887
  • 23 Hulsmans F H, Tio T L, Mathus-Vliegen E MH. Colorectal villous adenoma: transrectal US in screening for invasive malignancy.  Radiology . 1992;  185 193-196
  • 24 Adams W J, Wong W D. Endorectal ultrasonic detection of malignancy within rectal villous lesions.  Dis Colon Rectum . 1995;  38 1093-1096
  • 25 Pikarsky A, Wexner S, Lebensart P. The use of rectal ultrasound for the correct diagnosis and treatment of rectal villous tumors.  Am J Surg . 2000;  179 261-265
  • 26 Kusunoki M, Yanagari H, Gondoh N. Use of transrectal ultrasonography to select type of surgery for villous tumors in the lower two thirds of the rectum.  Arch Surg . 1996;  131 714-717
  • 27 Schnall M D, Furth E E, Rosato E F, Kressel H Y. Rectal tumor stage: correlation of endorectal MR imaging and pathologic findings.  Radiology . 1994;  190 709-714
  • 28 Meyenberger C, Huch Boni A R, Bertschinger P. Endoscopic ultrasound and endorectal magnetic resonance imaging: a prospective, comparative study for preoperative staging and follow-up of rectal cancer.  Endoscopy . 1995;  27 469-479
  • 29 Vogl T J, Pegios W, Mack M G. AJR .  1997;  168 1427-1434
  • 30 Mathus-Vleigen E MH, Tytgat G N. Nd:YAG Laser photocoagulation in colorectal adenoma. Evaluation of its safety, usefulness, and efficacy.  Gastroenterol . 1986;  90 1865-1873
  • 31 Aubert A, Meduri B, Fritsch J. Endoscopic treatment by snare electrocoagulation prior to Nd:YAG laser photocoagulation in 85 voluminous colorectal villous adenomas.  Dis Colon Rectum . 1991;  34 372-377
  • 32 Brunetaud J M, Mosquet L, Houcke M. Villous adenomas of the rectum. Results of endoscopic treatment with argon and Nd:YAG lasers.  Gastroenterol. 85-89 832-897
  • 33 Low D E, Kozarek R A, Ball T J, Ryan J A. Nd-YAG laser photoablation of sessile villous and tubular adenomas of the colorectum.  Ann Surg . 1988;  208 725-732
  • 34 Hyser M J, Gau F C. Endoscopic Nd:YAG laser therapy for villous adenomas of the colon and rectum.  Am Surg . 1996;  62 577-580
  • 35 Zlatanic J, Waye J D, Kim P S. Large sessile colonic adenomas: use of argon plasma coagulator to supplement piecemeal snare polypectomy.  Gastrointest Endosc . 1999;  49 731-735
  • 36 Mlkvy P, Messmann H, Regula J. Photodynamic therapy for gastrointestinal tumors using three photosensitizers-ALA induced PPIX, photofrin and MTHPC. A pilot study.  Neoplasma . 1998;  45 157-161
  • 37 Parks A G, Stuart A E. The management of villous tumours of the large bowel.  Br J Surg . 1973;  60 688-695
  • 38 Muldoon J P, Capehart R J. Two scope technique for the transrectal removal of lesions high in the rectum and sigmoid colon.  Surg Gynecol Obstet . 1973;  137 1019-1022
  • 39 Miskowiak J, Lindenberg S. Excision of rectal villous adenomas using a TA or GIA stapler.  Br J Surg . 1986;  73 630
  • 40 DeGennaro V A, Lescher T C. Transanal excision of rectal tumors using a laparoscopic stapler.  Dis Colon Rectum . 1995;  38 327
  • 41 Pollard S G, Mac Farlane R, Everett W G. Villous tumors of the large bowel.  Br J Surg . 1988;  75 910-912
  • 42 Sakamoto G D, MacKeigan J M, Senagore A J. Transanal excision of large, rectal villous adenomas.  Dis Colon Rectum . 1991;  34 880-885
  • 43 Heimann T M, Oh C, Steinhager R M. Surgical treatment of tumors of the distal rectum with sphincter preservation.  Ann Surg . 1992;  216 432-436
  • 44 Vargas H D, Beck D E, Opelka F G. Recurrence of rectal villous adenoma following transanal excision.  Perspectives in Colon and Rectal Surgery . 2000;  13 7-16
  • 45 Bartman A E, Sanderson S J, Ewing S L. Aberrant expression of MUC5AC and MUC6 gastric mucin genes in colorectal polyps.  Int J Cancer . 1999;  80 210-218
  • 46 Buisine M P, Janin A, Maunory V. Aberrant expression of a human mucin gene (MUC5AC) in rectosigmoid villous adenoma.  Gastroenterology . 1996;  110 84-91
  • 47 Longman R J, Sylvester P A, O'Leary D. Lack of mucin MUC5AC field change expression associated with tubulovillous and villous colorectal adenomas.  J Clin Pathol . 2000;  53 100-104
  • 48 Buess G, Kipfmuller K, Ibald R. Clinical results of transanal endoscopic microsurgery.  Surg Endosc . 1988;  2 245-250
  • 49 Lev-Chelouche D, Margel D, Goldman G, Rabau M J. Transanal endoscopic microsurgery. Experience with 75 rectal neoplasms.  Dis Colon Rectum . 2000;  43 662-668
  • 50 Sacclarides T J. Transanal endoscopic microsurgery.  Surg Clin North Am . 1997;  77 229-239
  • 51 Wilson S E, Gordon H E. Excision of rectal lesions by the Kraske approach.  Am J Surg . 1969;  118 213-217
  • 52 Klingensmith W, Dickenson W E, Hays R S. Posterior resection of selected rectal tumors.  Arch Surg . 1975;  110 647-651
  • 53 Jorgensen S J, Ottsen M. Posterior rectotomy for villous tumours of the rectum.  Acta Chir Scand . 1975;  141 680-682
  • 54 Arnaud J P, Eloy M R, Clendinnen G, Adloff M. The posterior approach for villous tumors of the rectum.  Am J Surg . 1978;  136 273-275
  • 55 Christiansen J. Excision of mid-rectal lesions by the Kraske sacral approach.  Br J Surg . 1980;  651-652
  • 56 Bergamaschi R, Arnaud J P. Management of large encircling mid-rectal adenomas in frail patients.  Int J Colorect Dis . 1995;  10 53-54
  • 57 Kusunoki M, Yanagi H, Shoji Y. Staple anastomosis for trans-sphincteric resection of the rectum.  Surg Gynecol Obstet . 1991;  173 325-326
  • 58 Mason A Y. Trans-sphincteric surgery of the rectum.  Prog Surg . 1974;  13 66-97
  • 59 Oh C, Kark A E. The transsphinteric approach to mid and low rectal villous adenoma: anatomic basis of surgical treatment.  Ann Surg . 1972;  176 605-612
  • 60 Criado F J, Wilson T H. Posterior transsphincteric approach for surgery of the rectum: the Bevan operation.  Dis Colon Rectum . 1981;  24 145-150
  • 61 Heij H A, Tan K G, Van Houten H. The transsphincteric approach to rectal villous adenomas.  Neth J Surg . 1982;  34 4-7
  • 62 Thompson B W, Tucker E. Transsphincteric approach to lesions of the rectum.  South Med J . 1987;  80 41-43
  • 63 Westbrook K C, Lang N P, Broadwater J R, Thompson B W. Posterior surgical approaches to the rectum.  Ann Surg . 1982;  195 677-685
  • 64 Heberer G, Denecke H, Pratschke E. Anterior and low anterior resection.  World J Surg . 1982;  6 517-524
  • 65 Redmond H P, Austin O MB, Deasy J M. Safety of double-stapled anastomosis in low anterior resection.  Br J Surg . 1993;  80 924-927
  • 66 Manson P N, Carmen M L, Collar J A, Veidenheimer M C. Anterior resection for adenocarcinoma-Lahey Clinic experience from 1963 through 1969.  Am J Surg . 1976;  131 434-441
  • 67 Smith L E. Anastomosis with EEA stapler after anterior colonic resection.  Dis Colon Rectum . 1981;  24 236-242
  • 68 Lewis W G, Martin I G, Williamson M ER. Why do some patients experience poor functional results after anterior resection of the rectum for carcinoma?.  Dis Colon Rectum . 1995;  38 259-263
  • 69 Karanijia N D, Schache D J, Heald R J. Function of the distal rectum after low anterior resection for carcinoma.  Br J Surg . 1992;  79 114-116
  • 70 Cohen A M, Enker W E, Minsky B D. Proctectomy and coloanal reconstruction for rectal cancer.  Dis Colon Rectum . 1990;  33 40-43
  • 71 Enker W E, Steams Jr W M, Janov A J. Perianal coloanal anastomosis following anterior resection for rectal carcinoma.  Dis Colon Rectum . 1985;  28 576-581
  • 72 Hautefeuille P, Valleur P, Perniceni T. Functional and oncologic results after coloanal anastomosis for low rectal carcinoma.  Ann Surg . 1988;  207 61-64
  • 73 Paty P B, Encker W E, Cohen A M. Long term functional results of coloanal anastomosis for rectal cancer.  Am J Surg . 1994;  167 90-95
  • 74 Rudd W H. The transanal anastomosis: a sphincter saving operation with improved continence.  Dis Colon Rectum . 1979;  22 102-105
  • 75 Vernava III M A, Robbins P L, Brabbee G W. Restorative resection. Coloanal anastomosis for benign and malignant disease.  Dis Colon Rectum . 1989;  32 690-693
  • 76 Hallbrook O, Pahlman L, Krog M. Randomized comparison of straight and colonic J pouch anastomosis after lower anterior resection.  Ann Surg . 1996;  224 58-65
  • 77 Seow-Choen F, Goh H S. Prospective randomized trial comparing J colonic pouch-anal anastomosis and straight coloanal reconstruction.  Br J Surg . 1995;  82 608-610
  • 78 Wang J-Y, You Y-T, Chen H-W. Stapled colonic J pouch anal anastomosis without a diverting colostomy for rectal carcinoma.  Dis Colon Rectum . 1997;  40 30-34
  • 79 Hida J, Yasutumi M, Fujimoto K. Functional outcome after low anterior resection for rectal cancer using the colonic J-pouch; prospective randomized study for determination of optimum pouch size.  Dis Colon Rectum . 1996;  39 986-991
  • 80 Schapiro S. Villous papilloma of the rectum and colon.  Dis Colon Rectum . 1965;  91 362-370
  • 81 Chiu Y S, Spencer R J. Villous lesions of the colon.  Dis Colon Rectum . 1978;  21 493-495
  • 82 Kronberg O, Kramhoft J, Backer O. Early complications following operations for cancer of the rectum and anus.  Dis Colon Rectum . 1974;  17 741-749
  • 83 Rothenberger D A, Wong W D. Abominoperineal resection for adnenocarcinoma of the low rectum.  World J Surg . 1992;  16 478-485