Tissue Engineering of Heart Valves - Current Aspects

U. A. Stock; J. P. Vacanti; J. E. Mayer Jr; T. Wahlers

doi:10.1055/s-2002-32406

The Thoracic and Cardiovascular Surgeon, Table of Contents

Thorac Cardiovasc Surg 2002; 50(3): 184-193
DOI: 10.1055/s-2002-32406

Review

Tissue Engineering of Heart Valves - Current Aspects

U. A. Stock¹ , J. P. Vacanti^2, ³ , J. E. Mayer Jr.⁴ , T. Wahlers¹

¹Department of Thoracic and Cardiovascular Surgery, Friedrich-Schiller-University, Jena, Germany
²Department of Surgery, Massachusetts General Hospital, Harvard Medical School, Boston, USA
³Center for the Integration of medicine and Innovative Technologies, Harvard Medical School, Boston, USA
⁴Department of Cardiovascular Surgery, Children's Hospital, Harvard Medical School, Boston, USA

Abstract

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Abstract

Tissue engineering of heart valves is an evolving research field. Driven by the shortcomings of the heart valve substitutes currently available, such as need for anticoagulation, susceptibility to infections, inability to grow and autorepair, the multidisciplinary approach for designing and growing viable heart valves identical to the native heart valves has begun. The following will give an update of the recent developments, current limitations and potential future applications of tissue-engineered heart valves.

Key words

Tissue Engineering - Heart valves - Scaffold - Autologous cells

Full Text

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MD Ulrich A. Stock

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